Recent advances in the synthesis of α-amino ketones

LAT Allen, RC Raclea, P Natho… - Organic & Biomolecular …, 2021 - pubs.rsc.org
Due to the importance of the amino ketone motif in synthetic and medicinal chemistry, the
number of protocols developed in recent years has considerably increased. This review …

Visible‐light‐driven α‐Oxidation of Amide C(sp3)−H Bonds to Imides via N‐Bromosuccinimide and Water

HH Chang, XX He, ZL Zang, CH Zhou… - Asian Journal of …, 2022 - Wiley Online Library
An efficient, metal‐free oxidation method of the N‐ortho C (sp3)− H bond of amide via visible‐
light irradiation has been developed. A broad range of imides can be facilely obtained at …

Thiourea-mediated halogenation of alcohols

AR Mohite, RS Phatake, P Dubey… - The Journal of …, 2020 - ACS Publications
The halogenation of alcohols under mild conditions expedited by the presence of
substoichiometric amounts of thiourea additives is presented. The amount of thiourea added …

N-Halosuccinimides as Precatalysts for C-, N-, O-, and X-Nucleophilic Substitution Reactions of Alcohols under Mild Reaction Conditions

N Ajvazi, S Stavber - Catalysts, 2020 - mdpi.com
N-halosuccinimides (chloro, bromo, and iodo, respectively) were introduced, tested, and
applied as efficient and non-metal precatalysts for C-, N-, O-, and X-nucleophilic substitution …

NBS-mediated synthesis of β-keto sulfones from benzyl alcohols and sodium arenesulfinates

M Muneeswara, N Sundaravelu, G Sekar - Tetrahedron, 2019 - Elsevier
An efficient synthetic route towards the synthesis of β-keto sulfones has been developed
from secondary benzyl alcohols using N-bromosuccinimide (NBS). The present protocol …