Peripheral nerve injury (PNI) is currently recognized as one of the most significant public
health issues and affects the general well‐being of millions of individuals worldwide …

After spinal cord injury, tissue distal to the lesion contains undamaged cells that could
support or augment recovery. Targeting these cells requires a clearer understanding of their …

Peripheral nerve injury (PNI) is common and, unlike damage to the central nervous system
injured nerves can effectively regenerate depending on the location and severity of injury …

Peripheral sensory neurons regenerate their axon after nerve injury to enable functional
recovery. Intrinsic mechanisms operating in sensory neurons are known to regulate nerve …

Sensory neurons located in dorsal root ganglia (DRG) convey sensory information from
peripheral tissue to the brain. After peripheral nerve injury, sensory neurons switch to a …

Activating Transcription Factor 3 (ATF3) is upregulated in reaction to several cellular
stressors found in a wide range of pathological conditions to coordinate a transcriptional …

Peripheral nerve regeneration is associated with pain in several preclinical models of
neuropathic pain. Some neuropathic pain conditions and preclinical neuropathic pain …

In postmitotic neurons, several tumor suppressor genes (TSGs), including p53, Rb, and
PTEN, modulate the axon regeneration success after injury. Particularly, PTEN inhibition is a …

After spinal cord injury (SCI), the “spared” tissue below the lesion contains undamaged cells
that could support or augment recovery, but targeting these cells requires a clearer …

Following acute injury, the capillary vascular bed in the lung must be repaired to reestablish
gas exchange with the external environment. Little is known about the transcriptional and …