Cancer radio-immunotherapy, integrating external/internal radiation therapy with immuno-
oncology treatments, emerges in the current management of cancer. A growing number of …

Cancer immunotherapy has transformed traditional treatments, with immune checkpoint
blockade being particularly prominent. However, immunotherapy has minimal benefit for …

The tumor immune microenvironment is a determinant of response to cancer
immunotherapy and, in many cases, is prognostic for patient survival independently of the …

Simple Summary In breast cancer, there is a high degree of variability in tumors and the
surrounding tissue called the tumor microenvironment (TME). To better understand tumor …

Simple Summary Oxygen-guided radiotherapy is a new modality for cancer irradiation.
Spatially Fractionated Radiation Therapy allows the treatment of hypoxic tumor areas with …

Spatial transcriptional profiling provides gene expression information within the important
anatomical context of tissue architecture. This approach is well suited to characterizing solid …

PSMA is a transmembrane protein that is markedly overexpressed in prostate cancer,
making it an excellent target for imaging and treating patients with prostate cancer. Several …

Abstract Background Immune checkpoint inhibitors (ICIs) have demonstrated promising
outcomes in small cell lung cancer (SCLC), but not all patients benefit from it. Thus …

Radiotherapy (RT) is the standard-of-care treatment for more than half of cancer patients
with localized tumors and is also used as palliative care to facilitate symptom relief in …

Immune checkpoint inhibitors (ICIs) induce a durable response in a wide range of tumor
types, but only a minority of patients outside these 'responsive'tumor types respond, with …