Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline

S Bhasin, GR Cunningham, FJ Hayes… - The Journal of …, 2010 - academic.oup.com
Objective: Our objective was to update the guidelines for the evaluation and treatment of
androgen deficiency syndromes in adult men published previously in 2006. Participants …

Testosterone replacement therapy and cardiovascular risk

T Gagliano-Jucá, S Basaria - Nature Reviews Cardiology, 2019 - nature.com
Testosterone is the main male sex hormone and is essential for the maintenance of male
secondary sexual characteristics and fertility. Androgen deficiency in young men owing to …

Evaluation and management of testosterone deficiency: AUA guideline

JP Mulhall, LW Trost, RE Brannigan, EG Kurtz… - The Journal of …, 2018 - auajournals.org
Purpose: There has been a marked increase in testosterone prescriptions in the past
decade resulting in a growing need to give practicing clinicians proper guidance on the …

Endogenous testosterone and mortality in men: a systematic review and meta-analysis

AB Araujo, JM Dixon, EA Suarez… - The Journal of …, 2011 - academic.oup.com
Context: Low testosterone levels have been associated with outcomes that reduce survival
in men. Objective: Our objective was to perform a systematic review and meta-analysis of …

The Princeton III Consensus recommendations for the management of erectile dysfunction and cardiovascular disease

A Nehra, G Jackson, M Miner, KL Billups… - Mayo Clinic …, 2012 - Elsevier
Abstract The Princeton Consensus (Expert Panel) Conference is a multispecialty
collaborative tradition dedicated to optimizing sexual function and preserving cardiovascular …

Testosterone treatment and mortality in men with low testosterone levels

MM Shores, NL Smith, CW Forsberg… - The Journal of …, 2012 - academic.oup.com
Context: Low testosterone levels in men have been associated with increased mortality.
However, the influence of testosterone treatment on mortality in men with low testosterone …

The role of androgens and estrogens on healthy aging and longevity

AM Horstman, EL Dillon, RJ Urban… - … Series A: Biomedical …, 2012 - academic.oup.com
Aging is associated with a loss of sex hormone in both men (andropause) and women
(menopause). In men, reductions in testosterone can trigger declines in muscle mass, bone …

Hypogonadism as a risk factor for cardiovascular mortality in men: a meta-analytic study

G Corona, G Rastrelli, M Monami… - European journal of …, 2011 - academic.oup.com
Objective To verify whether hypogonadism represents a risk factor for cardiovascular (CV)
morbidity and mortality and to verify whether testosterone replacement therapy (TRT) …

Dihydrotestosterone: biochemistry, physiology, and clinical implications of elevated blood levels

RS Swerdloff, RE Dudley, ST Page, C Wang… - Endocrine …, 2017 - academic.oup.com
Benefits associated with lowered serum DHT levels after 5 α-reductase inhibitor (5AR-I)
therapy in men have contributed to a misconception that circulating DHT levels are an …

Testosterone and insulin resistance in the metabolic syndrome and T2DM in men

PM Rao, DM Kelly, TH Jones - Nature Reviews Endocrinology, 2013 - nature.com
Obesity, type 2 diabetes mellitus and the metabolic syndrome are major risk factors for
cardiovascular disease. Studies have demonstrated an association between low levels of …