[12] aneN3-based lipid with naphthalimide moiety for enhanced gene transfection efficiency

YG Gao, U Alam, AX Ding, Q Tang, ZL Tan, YD Shi… - Bioorganic …, 2018 - Elsevier
Three cationic lipids derived from [12] aneN 3 modified with naphthalimide (1a), oleic acid
(1b) and octadecylamine (1c) were designed and synthesized. In vitro transfection showed …

Synthesis of bifunctional molecules containing [12] aneN 3 and coumarin moieties as effective DNA condensation agents and new non-viral gene vectors

P Yue, Y Zhang, ZF Guo, AC Cao, ZL Lu… - Organic & Biomolecular …, 2015 - pubs.rsc.org
A series of bifunctional molecules with different combinations of macrocyclic polyamine [12]
aneN3 and coumarin moieties, 4a/b and 5a/b, were synthesized by a two-step copper (I) …

Prenyl ammonium salts–new carriers for gene delivery: a B16-F10 mouse melanoma model

E Grecka, M Statkiewicz, A Gorska, M Biernacka… - PLoS …, 2016 - journals.plos.org
Purpose Prenyl ammonium iodides (Amino-Prenols, APs), semi-synthetic polyprenol
derivatives were studied as prospective novel gene transfer agents. Methods AP-7,-8,-11 …