[HTML][HTML] Diabetes mellitus and diabetic foot ulcer: Etiology, biochemical and molecular based treatment strategies via gene and nanotherapy

AVA Mariadoss, AS Sivakumar, CH Lee… - Biomedicine & …, 2022 - Elsevier
Diabetes mellitus (DM) is a collection of metabolic and pathophysiological disorders
manifested with high glucose levels in the blood due to the inability of β-pancreatic cells to …

[HTML][HTML] The prevalence of frailty and pre-frailty among geriatric hospital inpatients and its association with economic prosperity and healthcare expenditure: A …

P Doody, EA Asamane, JA Aunger, B Swales… - Ageing research …, 2022 - Elsevier
Background Frailty is a common and clinically significant condition among geriatric
populations. Although well-evidenced pooled estimates of the prevalence of frailty exist …

Comparative cardiovascular effectiveness and safety of SGLT-2 inhibitors, GLP-1 receptor agonists, and DPP-4 inhibitors according to frailty in type 2 diabetes

A Kutz, DH Kim, DJ Wexler, J Liu… - Diabetes …, 2023 - Am Diabetes Assoc
OBJECTIVE To evaluate the comparative cardiovascular effectiveness and safety of sodium–
glucose cotransporter 2 inhibitors (SGLT-2is), glucagon-like peptide 1 receptor agonists …

Frailty and cerebrovascular disease: concepts and clinical implications for stroke medicine

NR Evans, OM Todd, JS Minhas… - … Journal of Stroke, 2022 - journals.sagepub.com
Frailty is a distinctive health state in which the ability of older people to cope with acute
stressors is compromised by an increased vulnerability brought by age-associated declines …

[HTML][HTML] Frailty and risk of microvascular complications in patients with type 2 diabetes: a population-based cohort study

Y Wu, T Xiong, X Tan, L Chen - BMC medicine, 2022 - Springer
Background Cross-sectional studies found that frailty was associated with prevalent diabetic
microvascular complications (DMC). Longitudinal evidence in this regard is inconclusive …

Physical frailty, genetic predisposition, and incident Parkinson disease

Z Zheng, Y Lv, S Rong, T Sun, L Chen - JAMA neurology, 2023 - jamanetwork.com
Importance Cross-sectional evidence implicates high prevalent frailty in patients with
Parkinson disease (PD), whereas the longitudinal association remains unknown. Objectives …

[HTML][HTML] Association of frailty with the incidence risk of cardiovascular disease and type 2 diabetes mellitus in long-term cancer survivors: a prospective cohort study

X Cao, Z Yang, X Li, C Chen, EO Hoogendijk, J Zhang… - BMC medicine, 2023 - Springer
Background Comorbidities among cancer survivors remain a serious healthcare burden and
require appropriate management. Using two widely used frailty indicators, this study aimed …

[HTML][HTML] An analysis of frailty and multimorbidity in 20,566 UK Biobank participants with type 2 diabetes

P Hanlon, BD Jani, E Butterly, B Nicholl… - Communications …, 2021 - nature.com
Background Frailty and multimorbidity are common in type 2 diabetes (T2D), including
people< 65 years. Guidelines recommend adjustment of treatment targets in people with …

Clinical impacts of frailty on 123,172 people with diabetes mellitus considering the age of onset and drugs of choice: a nationwide population-based 10-year trajectory …

ST Huang, LK Chen, FY Hsiao - Age and ageing, 2023 - academic.oup.com
Aims Frailty substantially increased the risk of adverse clinical outcomes, which was also
critical in diabetes management. This study aimed to investigate the interrelationships …

Cognitive Frailty and Functional Disability among Community-Dwelling older adults: a systematic review

KF Tang, PL Teh, SWH Lee - Innovation in Aging, 2023 - academic.oup.com
Abstract Background and Objectives This review aimed to summarize the association
between cognitive frailty (presence of frailty and cognitive impairment) and the risk of …