Potassium channels in vascular smooth muscle: a pathophysiological and pharmacological perspective

MF Dogan, O Yildiz, SO Arslan… - Fundamental & clinical …, 2019 - Wiley Online Library
Potassium (K+) ion channel activity is an important determinant of vascular tone by
regulating cell membrane potential (MP). Activation of K+ channels leads to membrane …

[PDF][PDF] A review of benzopyran derivatives in pharmacotherapy of breast cancer

K Piyush, S Kuldeep, RM Azizur… - Asian J Pharm Clin …, 2018 - researchgate.net
One of the naturally occurring compounds containing oxygen moiety is benzopyran.
Depending on its substitution pattern, different biological effects are shown. The benzopyran …

Preparation of a Pt(II)–3-Hydroxy-2-tolyl-4H-chromen-4-one Complex Having Antimicrobial, Anticancerous, and Radical Scavenging Activities with Related …

M Mohmad, N Agnihotri, V Kumar, M Azam, R Kamal… - ACS …, 2023 - ACS Publications
A novel benzopyran-based platinum (II)–3-hydroxy-2-tolyl-4 H-chromen-4-one (HToC)
complex has been prepared and studied by UV–visible spectrophotometry. The study is …

Low-Dose Radiation Reduces Doxorubicin-Induced Myocardial Injury Through Mitochondrial Pathways

D Zhao, X Jiang, X Meng, D Liu, Y Du… - Dose …, 2023 - journals.sagepub.com
The use of doxorubicin (DOX) as an anthraquinone antineoplastic agent is limited due to its
cardiotoxicity. Our previous study suggested that low-dose radiation (LDR) could mitigate …

Synthesis, structures, and anticancer potentials of four platinum (II) complexes with benzopyran derivatives targeting mitochondria

JH Liu, ZZ Wei, L Yang, QP Qin, XX Liu… - Inorganic Chemistry …, 2020 - Elsevier
Four new benzopyran-platinum (Pt) complexes,[Pt (C1) Cl 2]⋅ CH 3 OH (C1-Pt),[Pt (C2) Cl
2](C2-Pt),[Pt (C3) Cl 2](C3-Pt), and [Pt (C4) Cl 2](C4-Pt) with 3-(1H-benzo [d] imidazol-2-yl) …

Medicinal chemistry of potassium channel modulators: An update of recent progress (2011-2017)

VK Vyas, P Parikh, J Ramani… - Current Medicinal …, 2019 - ingentaconnect.com
Background: Potassium (K+) channels participate in many physiological processes, cardiac
function, cell proliferation, neuronal signaling, muscle contractility, immune function …

The Literature of Heterocyclic Chemistry, Part XIII, 2012–2013

LI Belen'kii, YB Evdokimenkova - Advances in Heterocyclic Chemistry, 2015 - Elsevier
A systematized review of reviews and monographs published in 2012–2013 on all aspects
of heterocyclic chemistry is given.

Three-component reaction and organocatalysis in one: Synthesis of densely substituted 4-aminochromanes

J Svĕtlík, N Prónayová, V Frecer, D Cież - Tetrahedron, 2016 - Elsevier
Cyclocondensation of salicylaldehydes with alkyl acetoacetates and 2-aminobenzothiazoles
or 2-amino-thiadiazole/thiazoles under l-proline catalysis gives 4-hetarylamino substituted …

HER2 inhibition efficiency of 6-amino-2-methyl-2-phenethyl-2 H-benzopyran and feasibility of the 64 Cu-labeled benzopyran derivative in cancer diagnosis

S Jung, JR Anusha, S Park, KH Yu, CJ Raj… - New Journal of …, 2019 - pubs.rsc.org
A series of benzopyran derivatives were synthesised, and the target product, 6-amino-2-
methyl-2-phenethyl-2H-benzopyran (compound 4), was labeled with radioactive 64Cu …

[PDF][PDF] Potassium Channels in Vascular Smooth Muscle: A Pathophysiological and Pharmacological Perspective

O YILDIZ - academia.edu
Potassium (K+) ion channel activity is an important determinant of vascular tone by
regulating cell membrane potential (MP). Activation of K+ channels leads to membrane …