Adolescent drug exposure: A review of evidence for the development of persistent changes in brain function

H Salmanzadeh, SM Ahmadi-Soleimani… - Brain research …, 2020 - Elsevier
Over the past decade, many studies have indicated that adolescence is a critical period of
brain development and maturation. The refinement and maturation of the central nervous …

Consequences of adolescent use of alcohol and other drugs: Studies using rodent models

LP Spear - Neuroscience & Biobehavioral Reviews, 2016 - Elsevier
Studies using animal models of adolescent exposure to alcohol, nicotine, cannabinoids, and
the stimulants cocaine, 3, 4-methylenedioxymethampethamine and methamphetamine have …

Mechanisms of action and persistent neuroplasticity by drugs of abuse

ER Korpi, B den Hollander, U Farooq… - Pharmacological …, 2015 - ASPET
Adaptation of the nervous system to different chemical and physiologic conditions is
important for the homeostasis of brain processes and for learning and remembering …

The impact of exposure to cannabinoids in adolescence: insights from animal models

T Rubino, D Parolaro - Biological psychiatry, 2016 - Elsevier
The regular use of cannabis during adolescence is of particular concern because use by this
age group seems to be associated with an increased likelihood of deleterious …

Long-term consequences of adolescent cannabinoid exposure in adult psychopathology

J Renard, MO Krebs, G Le Pen, TM Jay - Frontiers in neuroscience, 2014 - frontiersin.org
Marijuana is the most widely used illicit drug among adolescents and young adults. Unique
cognitive, emotional, and social changes occur during this critical period of development …

Chronic exposure to cannabinoids during adolescence but not during adulthood impairs emotional behaviour and monoaminergic neurotransmission

FR Bambico, NT Nguyen, N Katz, G Gobbi - Neurobiology of disease, 2010 - Elsevier
The pathophysiological neural mechanism underlying the depressogenic and anxiogenic
effects of chronic adolescent cannabinoid use may be linked to perturbations in …

Adolescent exposure to cannabis as a risk factor for psychiatric disorders

T Rubino, E Zamberletti… - Journal of …, 2012 - journals.sagepub.com
Adolescence represents a critical period for brain development and the endocannabinoid
system plays a crucial role in the regulation of neuronal refinement during this period …

The long-term cognitive consequences of adolescent exposure to recreational drugs of abuse

SM Mooney-Leber, TJ Gould - Learning & memory, 2018 - learnmem.cshlp.org
During adolescence, the brain continues to undergo vital developmental processes. In turn,
complex behavioral and cognitive skills emerge. Unfortunately, neurobiological …

Long-term consequences of perinatal and adolescent cannabinoid exposure on neural and psychological processes

A Higuera-Matas, M Ucha, E Ambrosio - Neuroscience & Biobehavioral …, 2015 - Elsevier
Marihuana is the most widely consumed illicit drug, even among adolescents and pregnant
women. Given the critical developmental processes that occur in the adolescent and fetal …

Chronic cannabinoid exposure during adolescence leads to long-term structural and functional changes in the prefrontal cortex

J Renard, T Vitalis, M Rame, MO Krebs, Z Lenkei… - European …, 2016 - Elsevier
In many species, adolescence is a critical phase in which the endocannabinoid system can
regulate the maturation of important neuronal networks that underlie cognitive function …