Light stimulus responsive nanomedicine in the treatment of oral squamous cell carcinoma

H Fan, Z Zhu, W Zhang, Y Yin, Y Tang, X Liang… - European journal of …, 2020 - Elsevier
Light stimulus responsive therapies are based on a variety of low-toxic therapeutic agents
and produce anti-tumor effects only under external light stimulation, thus greatly reducing …

[HTML][HTML] Progress in nanocarriers codelivery system to enhance the anticancer effect of photodynamic therapy

YL Yang, K Lin, L Yang - Pharmaceutics, 2021 - mdpi.com
Photodynamic therapy (PDT) is a promising anticancer noninvasive method and has great
potential for clinical applications. Unfortunately, PDT still has many limitations, such as …

[HTML][HTML] Photoacoustic nanodroplets for oxygen enhanced photodynamic therapy of cancer

M Xavierselvan, J Cook, J Duong, N Diaz, K Homan… - Photoacoustics, 2022 - Elsevier
Photodynamic therapy (PDT) is a well-known cancer therapy that utilizes light to excite a
photosensitizer and generate cytotoxic reactive oxygen species (ROS). The efficacy of PDT …

Superior Photophysical and Photosensitizing Properties of Nanoaggregates of Weakly Emissive Dyes for Use in Bioimaging and Photodynamic Therapy

AH Dar, A Ahmad, A Kumar, V Gowri, C Jori… - …, 2023 - ACS Publications
The development of luminescent dyes based on 1, 1, 4, 4-tetracyanobuta-1, 3-dienes
(TCBDs) is an active research area, and a quantum yield (ΦF) of 7.8% has been achieved …

Spotlight on Photoactivatable Liposomes beyond Drug Delivery: An Enabler of Multitargeting of Molecular Pathways

MA Saad, T Hasan - Bioconjugate chemistry, 2022 - ACS Publications
The potential of photoactivating certain molecules, photosensitizers (PS), resulting in
photochemical processes, has long been realized in the form of photodynamic therapy …

[HTML][HTML] Optimizing Axial and Peripheral Substitutions in Si-Centered Naphthalocyanine Dyes for Enhancing Aqueous Solubility and Photoacoustic Signal Intensity

MA Saad, R Pawle, S Selfridge, L Contreras… - International Journal of …, 2023 - mdpi.com
Photoacoustic imaging using external contrast agents is emerging as a powerful modality for
real-time molecular imaging of deep-seated tumors. There are several chromophores, such …

Dual function antibody conjugates for multimodal imaging and photoimmunotherapy of cancer cells

MA Saad, M Xavierselvan, HA Sharif… - Photochemistry and …, 2022 - Wiley Online Library
Precision imaging, utilizing molecular targeted agents, is an important tool in cancer
diagnostics and guiding therapies. While there are limitations associated with single mode …

[HTML][HTML] MOLECULAR AND NANOPARTICULATE AGENTS FOR PHOTODYNAMIC THERAPY GUIDED BY NEAR INFRARED IMAGING

A Grebinyk, O Chepurna, M Frohme, J Qu… - … of Photochemistry and …, 2024 - Elsevier
Photodynamic therapy (PDT) of cancer is a clinically approved, minimally invasive
therapeutic approach, combining PDT drug (photosensitizer, PS), molecular oxygen and …

Nitroreductase-Induced Aggregation of Gold Nanoparticles for “Off–On” Photoacoustic Imaging of Tumor Hypoxia

X Li, X Fang, S Li, KH Lui, WS Lo, Y Gu… - Journal of Biomedical …, 2021 - ingentaconnect.com
Hypoxia is an important phenomenon due to insufficient oxygen supply in tumor tissue, and
nitroreductase (NTR) is a characteristic enzyme used for evaluating hypoxia level in tumors …

Focused ultrasound-augmented cancer phototheranostics using albumin–indocyanine green nanoparticles

L Zhong, B Chen, J He, M He, Q Zhao, B Wang - Ultrasound in Medicine & …, 2021 - Elsevier
The purpose of this study was to develop a nanoparticle (NP) drug-loading system that
enhances the efficiency of indocyanine green (ICG) entry into the tissue under focused …