In recent years, the role of lipids in health and disease has received increasing attention. A
number of pathological conditions caused by exposure to xenobiotics or toxic chemicals are …

Two main subjects of erythrocyte rheology, deformation and aggregation, are discussed in
detail, on the basis of biochemical structure. The close relationship between the life span (or …

Exposure of red blood cells to oxygen radicals can induce hemoglobin damage and
stimulate protein degradation, lipid peroxidation, and hemolysis. To determine if these …

We have suggested that red blood cell proteolytic systems can degrade oxidatively
damaged proteins, and that both damage and degradation are independent of lipid …

Vitamin B6 (pyridoxine) supplementation has been found beneficial in preventing diabetic
neuropathy and retinopathy, and the glycosylation of proteins. Oxygen radicals and …

In recent years it has become clear that various free radicals and related oxidants can cause
serious damage to intracellular enzymes and other proteins. Several investigators have …

This study has examined the occurrence of lipid peroxidation in in vivo aged human
erythrocyte membranes. Erythrocytes of various ages were separated on discontinuous …

This review provides a summary of ongoing work in the area of red cell senescence. After
defining the problem in terms of questions that remain unanswered, we review the relevant …

Treatment of erythrocytes with the thiol-specific oxidant azodicarboxylic acid bis
(dimethylamide)(diamide) enhances their phagocytosis by adherent monocytes …

In banked human erythrocytes (RBCs), biochemical and functional changes are
accompanied with vesiculation and reduced in vivo survival. We hypothesized that some of …