Zebrafish as a robust preclinical platform for screening plant-derived drugs with anticonvulsant properties—a review

B Knap, D Nieoczym, U Kundap… - Frontiers in Molecular …, 2023 - frontiersin.org
Traditionally, selected plant sources have been explored for medicines to treat convulsions.
This continues today, especially in countries with low-income rates and poor medical …

Development of antiepileptic drugs throughout history: from serendipity to artificial intelligence

MG Corrales-Hernández, SK Villarroel-Hagemann… - Biomedicines, 2023 - mdpi.com
This article provides a comprehensive narrative review of the history of antiepileptic drugs
(AEDs) and their development over time. Firstly, it explores the significant role of serendipity …

[HTML][HTML] Epilepsy: Mitochondrial connections to the 'Sacred'disease

WH Moos, DV Faller, IP Glavas, I Kanara, K Kodukula… - Mitochondrion, 2023 - Elsevier
Over 65 million people suffer from recurrent, unprovoked seizures. The lack of validated
biomarkers specific for myriad forms of epilepsy makes diagnosis challenging. Diagnosis …

Knowledge, attitudes and practices towards epilepsy in morocco: A cross-sectional study

EB Hajji, B Traore, S Hassoune, S Bellakhdar… - Epilepsy & Behavior, 2024 - Elsevier
Background This study aims to assess knowledge, practices and attitudes of the general
Moroccan population towards epilepsy and to highlight predictive factors. Method A cross …

A real-world pharmacovigilance analysis of eslicarbazepine acetate using the FDA adverse events reporting system (FAERS) database from 2013 (Q4) to 2024 (Q1)

H Tang, J Xu, X Zhang, C Chen, G Song… - Frontiers in …, 2024 - frontiersin.org
Background The approval of eslicarbazepine acetate (ESL) by the Food and Drug
Administration (FDA) in 2013 marked an advancement in the treatment of adult patients with …

Epilepsy in Asian countries

A Adamu, R Chen, A Li, G Xue - Acta Epileptologica, 2023 - Springer
Epilepsy affects 50 million people worldwide. Nearly 80% of people with epilepsy live in
resource-constrained low-income and middle-income countries. In Asia, which has a …

Whole exome sequencing identified five novel variants in CNTN2, CARS2, ARSA, and CLCN4 leading to epilepsy in consanguineous families

AA Abdulkareem, Q Zaman, H Khan, S Khan… - Frontiers in …, 2023 - frontiersin.org
Introduction: Epilepsy is a group of neurological disorders characterized by recurring
seizures and fits. The Epilepsy genes can be classified into four distinct groups, based on …

[HTML][HTML] Epilepsy and deep brain stimulation of anterior thalamic nucleus

CD Perez-Malagon, MA Lopez-Gonzalez - Cureus, 2021 - ncbi.nlm.nih.gov
Presently, at least 60 million people are suffering from epilepsy worldwide. Although multiple
pharmacological options for treatment exist, about 30% to 40% of these patients are …

Stigma and psychosocial problems in patients with epilepsy

K Yeni - Exploration of Neuroscience, 2023 - explorationpub.com
Epilepsy, a prevalent neurological disorder, is characterized by chronic seizures resulting
from abnormal electrical activity in the brain. Adequate medical treatment allows roughly …

Knowledge, attitudes and practices of the Saudi population toward people with epilepsy: narrow or wide?

AA Al-Attas, OK Alshehri, AG Malhan, HM Alabdaly… - Acta Epileptologica, 2023 - Springer
Background Although epilepsy has been acknowledged as an illness since ancient time, the
public attitude toward epilepsy has not changed drastically due to the lack of appropriate …