Cyclic dinucleotides (CDNs) are highly versatile signalling molecules that control various
important biological processes in bacteria. The best-studied example is cyclic di-GMP (c-di …

The striking multiplicity, signal input diversity, and output specificity of c-di-GMP signaling
proteins in many bacteria has brought second messenger signaling back onto the agenda of …

It is critical for bacteria to recognize surface contact and initiate physiological changes
required for surface-associated lifestyles. Ubiquitous microbial appendages called pili are …

Bacterial biofilms can cause medical problems and issues in technical systems. While a
large body of knowledge exists on the phenotypes of planktonic and of sessile cells in …

Highlights•Motility appendages such as flagella and type IV pili (TFP) can participate in
surface sensing for a broad range of bacteria.•Surface sensing can involve both physical …

When bacteria encounter surfaces, they respond with surface colonization and virulence
induction. The mechanisms of bacterial mechanosensation and downstream signaling …

Bacteria thrive both in liquids and attached to surfaces. The concentration of bacteria on
surfaces is generally much higher than in the surrounding environment, offering bacteria …

Fundamental to all living organisms is the capacity to coordinate cell division and cell
differentiation to generate appropriate numbers of specialized cells. Whereas eukaryotes …

The complex life cycle of streptomycetes involves two distinct filamentous cell forms: the
growing (or vegetative) hyphae and the reproductive (or aerial) hyphae, which differentiate …

ABSTRACT The first International Symposium on c-Di-GMP Signaling in Bacteria (22 to 25
March 2015, Harnack-Haus, Berlin, Germany) brought together 131 molecular …