Amphibian skin is directly exposed to different environments. Amphibians interact with
environmental factors including microorganisms, parasites, predators, and physical factors …

The emergence of new pathogens and multidrug resistant bacteria is an important public
health issue that requires the development of novel classes of antibiotics. Antimicrobial …

Frog skin constitutes a rich source of peptides with a wide range of biological properties.
These include host-defense peptides with cytotoxic activities against bacteria, fungi …

Antimicrobial peptides, as an important member of the innate immune system, have various
biological activities in addition to antimicrobial activity. There are some AMPs with …

Ethnopharmacological relevance Hibiscus rosa-sinensis (HRS) is a tropical flowery plant,
widely distributed in Asian region and an important traditional medicine used in many …

Introduction: The emergence of multidrug-resistant microorganisms has necessitated a
search for new antimicrobial agents. Skin secretions of many frog species contain peptides …

Chytridiomycosis, the disease caused by the fungal pathogen Batrachochytrium
dendrobatidis (Bd), has devastated global amphibian biodiversity. Nevertheless, some hosts …

Antimicrobial peptides are the backbone of first-line defense against various
microorganisms in the animal kingdom. Thus, not surprisingly, they are gaining attention in …

Several frog skin peptides, first identified as result of their antimicrobial or
immunomodulatory activities, have subsequently been shown to stimulate insulin release …

Improvement of insulin secretion by pancreatic β-cells and preservation of their mass are the
current challenges that future antidiabetic drugs should meet for achieving efficient and long …