Neuromodulation in epilepsy: state-of-the-art approved therapies

P Ryvlin, S Rheims, LJ Hirsch, A Sokolov… - The Lancet …, 2021 - thelancet.com
Three neuromodulation therapies have been appropriately tested and approved in refractory
focal epilepsies: vagus nerve stimulation (VNS), deep brain stimulation of the anterior …

Cholinergic system changes in Parkinson's disease: emerging therapeutic approaches

NI Bohnen, AJ Yarnall, RS Weil, E Moro… - The Lancet …, 2022 - thelancet.com
In patients with Parkinson's disease, heterogeneous cholinergic system changes can occur
in different brain regions. These changes correlate with a range of clinical features, both …

Current directions in the auricular vagus nerve stimulation I–a physiological perspective

E Kaniusas, S Kampusch, M Tittgemeyer… - Frontiers in …, 2019 - frontiersin.org
Electrical stimulation of the auricular vagus nerve (aVNS) is an emerging technology in the
field of bioelectronic medicine with applications in therapy. Modulation of the afferent vagus …

Parametric characterization of neural activity in the locus coeruleus in response to vagus nerve stimulation

DR Hulsey, JR Riley, KW Loerwald… - Experimental …, 2017 - Elsevier
Vagus nerve stimulation (VNS) has emerged as a therapy to treat a wide range of
neurological disorders, including epilepsy, depression, stroke, and tinnitus. Activation of …

Safety, feasibility, and efficacy of vagus nerve stimulation paired with upper-limb rehabilitation after ischemic stroke

J Dawson, D Pierce, A Dixit, TJ Kimberley… - Stroke, 2016 - Am Heart Assoc
Background and Purpose—Recent animal studies demonstrate that vagus nerve stimulation
(VNS) paired with movement induces movement-specific plasticity in motor cortex and …

[HTML][HTML] Vagus nerve stimulation induces widespread cortical and behavioral activation

L Collins, L Boddington, PJ Steffan, D McCormick - Current Biology, 2021 - cell.com
Vagus nerve stimulation (VNS) is used for management of a variety of neurological
conditions, although the therapeutic mechanisms are not fully understood. Accumulating …

Clinical perspectives on vagus nerve stimulation: present and future

E Goggins, S Mitani, S Tanaka - Clinical Science, 2022 - portlandpress.com
The vagus nerve, the great wanderer, is involved in numerous processes throughout the
body and vagus nerve stimulation (VNS) has the potential to modulate many of these …

Transcutaneous vagus nerve stimulation boosts associative memory in older individuals

HIL Jacobs, JM Riphagen, CM Razat, S Wiese… - Neurobiology of …, 2015 - Elsevier
Direct vagus nerve stimulation (dVNS) is known to improve mood, epilepsy, and memory.
Memory improvements have been observed in Alzheimer's disease patients after long-term …

Targeted vagus nerve stimulation for rehabilitation after stroke

ND Engineer, TJ Kimberley, CN Prudente… - Frontiers in …, 2019 - frontiersin.org
Stroke is a leading cause of disability worldwide, and in approximately 60% of individuals,
upper limb deficits persist 6 months after stroke. These deficits adversely affect the functional …

Targeting plasticity with vagus nerve stimulation to treat neurological disease

SA Hays, RL Rennaker, MP Kilgard - Progress in brain research, 2013 - Elsevier
Pathological neural activity in a variety of neurological disorders could be treated by
directing plasticity to specifically renormalize aberrant neural circuits, thereby restoring …