Identification of RNA structures and their roles in RNA functions
The development of high-throughput RNA structure profiling methods in the past decade has
greatly facilitated our ability to map and characterize different aspects of RNA structures …
greatly facilitated our ability to map and characterize different aspects of RNA structures …
Revisiting the mesenchymal “stem vs. stromal” cell dichotomy and its implications for development of improved potency metrics
DG Phinney, R Hwa Lee, SV Boregowda - Stem Cells, 2023 - academic.oup.com
Mesenchymal stem/stromal cell (MSC)-based therapies have been evaluated in over 1500
human clinical trials for a diverse array of disease indication, but outcomes remain …
human clinical trials for a diverse array of disease indication, but outcomes remain …
Global analysis of protein-RNA interactions in SARS-CoV-2-infected cells reveals key regulators of infection
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus
disease 2019 (COVID-19). SARS-CoV-2 relies on cellular RNA-binding proteins (RBPs) to …
disease 2019 (COVID-19). SARS-CoV-2 relies on cellular RNA-binding proteins (RBPs) to …
Glutamyl-prolyl-tRNA synthetase regulates proline-rich pro-fibrotic protein synthesis during cardiac fibrosis
Rationale: Increased protein synthesis of profibrotic genes is a common feature in cardiac
fibrosis and heart failure. Despite this observation, critical factors and molecular …
fibrosis and heart failure. Despite this observation, critical factors and molecular …
A viral pan-end RNA element and host complex define a SARS-CoV-2 regulon
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
COVID-19, generates multiple protein-coding, subgenomic RNAs (sgRNAs) from a longer …
COVID-19, generates multiple protein-coding, subgenomic RNAs (sgRNAs) from a longer …
Unconventional RNA‐binding proteins step into the virus–host battlefront
M Garcia‐Moreno, AI Järvelin… - Wiley Interdisciplinary …, 2018 - Wiley Online Library
The crucial participation of cellular RNA‐binding proteins (RBPs) in virtually all steps of virus
infection has been known for decades. However, most of the studies characterizing this …
infection has been known for decades. However, most of the studies characterizing this …
Global analysis of RNA-binding protein dynamics by comparative and enhanced RNA interactome capture
JI Perez-Perri, M Noerenberg, W Kamel, CE Lenz… - Nature protocols, 2021 - nature.com
Interactions between RNA-binding proteins (RBPs) and RNAs are critical to cell biology.
However, methods to comprehensively and quantitatively assess these interactions within …
However, methods to comprehensively and quantitatively assess these interactions within …
Mechanistic target of rapamycin in regulating macrophage function in inflammatory cardiovascular diseases
MSC Mangione, J Wen, DJ Cao - Journal of molecular and cellular …, 2024 - Elsevier
The mechanistic target of rapamycin (mTOR) is evolutionarily conserved from yeast to
humans and is one of the most fundamental pathways of living organisms. Since its …
humans and is one of the most fundamental pathways of living organisms. Since its …
[HTML][HTML] Tumor associated macrophages transfer ceruloplasmin mRNA to fibrosarcoma cells and protect them from ferroptosis
Solid tumors are characterized by hypoxic areas, which are prone for macrophage
infiltration. Once infiltrated, macrophages polarize to tumor associated macrophages (TAM) …
infiltration. Once infiltrated, macrophages polarize to tumor associated macrophages (TAM) …
Baicalin Induces a Potent Innate Immune Response to Inhibit Respiratory Syncytial Virus Replication via Regulating Viral Non-Structural 1 and Matrix RNA
S Qin, X Huang, S Qu - Frontiers in Immunology, 2022 - frontiersin.org
Respiratory syncytial virus (RSV) infection is the most frequent cause of hospitalization in
pediatric patients. Current systemic treatment and vaccines are not curative and re-infection …
pediatric patients. Current systemic treatment and vaccines are not curative and re-infection …