Clinically significant bleeding can occur as a consequence of surgery, trauma, obstetric
complications, anticoagulation, and a wide variety of disorders of hemostasis. As the causes …

Preeclampsia remains till today a leading cause of maternal and fetal morbidity and
mortality. Pathophysiology of the disease is not yet fully elucidated, though it is evident that it …

Hereditary hemorrhagic telangiectasia (HHT, Osler-Weber-Rendu disease) is a rare
multisystem vascular disorder that causes chronic gastrointestinal bleeding, epistaxis, and …

Hereditary hemorrhagic telangiectasia (HHT) management is evolving because of the
emergence and development of antiangiogenic therapies to eliminate bleeding …

Background Excessive or abnormal mucocutaneous bleeding (MCB) may impact all aspects
of the physical and psychosocial wellbeing of those who live with it (PWMCB). The evidence …

Vascular anomalies represent a diverse group of disorders classified broadly as
malformations or tumors and include the second most common hereditary bleeding disorder …

Abstract Hereditary Hemorrhagic Telangiectasia (HHT) is a rare, autosomal dominant,
vascular disorder. About 80% of cases are caused by pathogenic variants in ACVRL1 (also …

One of the difficulties of pulp regeneration is the rapid vascularization of transplanted
engineered tissue, which is crucial for the initial survival of the graft and subsequent pulp …

In recent years, microphysiological system (MPS, also known as, organ-on-a-chip or tissue
chip) platforms have emerged with great promise to improve the predictive capacity of …

Background Hereditary haemorrhagic telangiectasia (HHT) is a rare hereditary multisystem
vascular disorder causing visceral arteriovenous malformations and mucocutaneous …