Ischemia/reperfusion injury (IRI) permeates a variety of diseases and is a ubiquitous
concern in every transplantation proceeding, from whole organs to modest grafts. Given its …

Methylene blue (MB) has received much attention in the perioperative and critical care
literature because of its ability to antagonize the profound vasodilation seen in distributive …

It is well known that during hepatic operative procedures, it is often critical that the irrigation
is interrupted to avoid possible bleeding, blood transfusions, variable intensities, and their …

As surgical and graft preservation techniques have improved and immunosuppressive drugs
have advanced, liver transplantation (LT) is now considered the gold standard for treating …

There has been considerable recent progress liver transplantation (LTX). The
postreperfusion syndrome has clearly defined and typically responds to vasopressin and/or …

Following burn, increased nitric oxide (NO) combine with superoxide anion forming
peroxynitrite. Methylene blue (MB) has NO blocking and antioxidant effects. Male Wistar rats …

Background and purpose In our study, we investigated the effects of methylene blue (MB) on
histopathological changes in renal ischemia/reperfusion (I/R) injury rat model. Material and …

Objective: A burn injury has two defined areas: central necrosis and an adjacent area of
ischaemia, which may or may not progress to necrosis. The concentration of nitric oxide …

After graft reperfusion in liver transplantation, ischemic reperfusion syndrome (IRS) is
characterized by persistent hypotension with low systemic vascular resistance. This …

Methylene blue (MB), a tricyclic phenothiazine compound, has been reported to exert
beneficial effects in experimental models of cerebral, hepatic, and intestinal …