Physics of viral dynamics

RF Bruinsma, GJL Wuite, WH Roos - Nature Reviews Physics, 2021 - nature.com
Viral capsids are often regarded as inert structural units, but in actuality they display
fascinating dynamics during different stages of their life cycle. With the advent of single …

Physical virology: From virus self‐assembly to particle mechanics

P Buzón, S Maity, WH Roos - Wiley Interdisciplinary Reviews …, 2020 - Wiley Online Library
Viruses are highly ordered supramolecular complexes that have evolved to propagate by
hijacking the host cell's machinery. Although viruses are very diverse, spreading through …

Adenovirus core protein V reinforces the capsid and enhances genome release from disrupted particles

N Martín-González, A Gómez-González… - Science …, 2023 - science.org
Out of the three core proteins in human adenovirus, protein V is believed to connect the
inner capsid surface to the outer genome layer. Here, we explored mechanical properties …

Artificial organelles: towards adding or restoring intracellular activity

RAJF Oerlemans, SBPE Timmermans… - …, 2021 - Wiley Online Library
Compartmentalization is one of the main characteristics that define living systems. Creating
a physically separated microenvironment allows nature a better control over biological …

Phage assembly and the special role of the portal protein

PE Prevelige Jr, JR Cortines - Current opinion in virology, 2018 - Elsevier
Virus infections are ultimately dependent on a successful viral genome delivery to the host
cell. The bacteriophage family Caudovirales evolved specialized machinery that fulfills this …

Mechanical tomography of an archaeal lemon-shaped virus reveals membrane-like fluidity of the capsid and liquid nucleoprotein cargo

M Cantero, V Cvirkaite-Krupovic… - Proceedings of the …, 2023 - National Acad Sciences
Archaeal lemon-shaped viruses have unique helical capsids composed of highly
hydrophobic protein strands which can slide past each other resulting in remarkable …

Structural and proteomic characterization of the initiation of giant virus infection

JR Schrad, JS Abrahão, JR Cortines, KN Parent - Cell, 2020 - cell.com
Since their discovery, giant viruses have expanded our understanding of the principles of
virology. Due to their gargantuan size and complexity, little is known about the life cycles of …

Structural polymorphism in protein cages and virus-like particles

F Lie, TN Szyszka, YH Lau - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Protein cages and virus-like particles are often thought of as highly uniform structures that
obey strict geometric rules for self-assembly. Yet, there is a growing number of examples …

Nanomechanical resilience and thermal stability of RSJ2 phage

U Sae-Ueng, C Bunsuwansakul, K Showpanish… - Scientific Reports, 2024 - nature.com
As the world moves toward a green economy and sustainable agriculture, bacterial viruses
or bacteriophages (phages) become attractive biocontrol agents for controlling crop …

Characterization of a primordial major capsid-scaffolding protein complex in icosahedral virus shell assembly

CR Davis, D Backos, MC Morais, MEA Churchill… - Journal of Molecular …, 2022 - Elsevier
Capsid assembly pathways are strongly conserved in the complex dsDNA viruses, where
major capsid proteins (MCP) self-assemble into icosahedral procapsid shells, chaperoned …