Physics of viral dynamics
Viral capsids are often regarded as inert structural units, but in actuality they display
fascinating dynamics during different stages of their life cycle. With the advent of single …
fascinating dynamics during different stages of their life cycle. With the advent of single …
Physical virology: From virus self‐assembly to particle mechanics
Viruses are highly ordered supramolecular complexes that have evolved to propagate by
hijacking the host cell's machinery. Although viruses are very diverse, spreading through …
hijacking the host cell's machinery. Although viruses are very diverse, spreading through …
Adenovirus core protein V reinforces the capsid and enhances genome release from disrupted particles
N Martín-González, A Gómez-González… - Science …, 2023 - science.org
Out of the three core proteins in human adenovirus, protein V is believed to connect the
inner capsid surface to the outer genome layer. Here, we explored mechanical properties …
inner capsid surface to the outer genome layer. Here, we explored mechanical properties …
Artificial organelles: towards adding or restoring intracellular activity
RAJF Oerlemans, SBPE Timmermans… - …, 2021 - Wiley Online Library
Compartmentalization is one of the main characteristics that define living systems. Creating
a physically separated microenvironment allows nature a better control over biological …
a physically separated microenvironment allows nature a better control over biological …
Phage assembly and the special role of the portal protein
PE Prevelige Jr, JR Cortines - Current opinion in virology, 2018 - Elsevier
Virus infections are ultimately dependent on a successful viral genome delivery to the host
cell. The bacteriophage family Caudovirales evolved specialized machinery that fulfills this …
cell. The bacteriophage family Caudovirales evolved specialized machinery that fulfills this …
Mechanical tomography of an archaeal lemon-shaped virus reveals membrane-like fluidity of the capsid and liquid nucleoprotein cargo
M Cantero, V Cvirkaite-Krupovic… - Proceedings of the …, 2023 - National Acad Sciences
Archaeal lemon-shaped viruses have unique helical capsids composed of highly
hydrophobic protein strands which can slide past each other resulting in remarkable …
hydrophobic protein strands which can slide past each other resulting in remarkable …
Structural and proteomic characterization of the initiation of giant virus infection
Since their discovery, giant viruses have expanded our understanding of the principles of
virology. Due to their gargantuan size and complexity, little is known about the life cycles of …
virology. Due to their gargantuan size and complexity, little is known about the life cycles of …
Structural polymorphism in protein cages and virus-like particles
F Lie, TN Szyszka, YH Lau - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Protein cages and virus-like particles are often thought of as highly uniform structures that
obey strict geometric rules for self-assembly. Yet, there is a growing number of examples …
obey strict geometric rules for self-assembly. Yet, there is a growing number of examples …
Nanomechanical resilience and thermal stability of RSJ2 phage
U Sae-Ueng, C Bunsuwansakul, K Showpanish… - Scientific Reports, 2024 - nature.com
As the world moves toward a green economy and sustainable agriculture, bacterial viruses
or bacteriophages (phages) become attractive biocontrol agents for controlling crop …
or bacteriophages (phages) become attractive biocontrol agents for controlling crop …
Characterization of a primordial major capsid-scaffolding protein complex in icosahedral virus shell assembly
Capsid assembly pathways are strongly conserved in the complex dsDNA viruses, where
major capsid proteins (MCP) self-assemble into icosahedral procapsid shells, chaperoned …
major capsid proteins (MCP) self-assemble into icosahedral procapsid shells, chaperoned …