[HTML][HTML] Polypharmacy in older adults: a narrative review of definitions, epidemiology and consequences

F Pazan, M Wehling - European geriatric medicine, 2021 - Springer
Background The number of older adults has been constantly growing around the globe.
Consequently, multimorbidity and related polypharmacy have become an increasing …

An overview of prevalence, determinants and health outcomes of polypharmacy

M Khezrian, CJ McNeil, AD Murray… - … advances in drug …, 2020 - journals.sagepub.com
A high rate of polypharmacy is, in part, a consequence of the increasing proportion of
multimorbidity in the ageing population worldwide. Our understanding of the potential harm …

An update on the clinical consequences of polypharmacy in older adults: a narrative review

JW Wastesson, L Morin, ECK Tan… - Expert opinion on drug …, 2018 - Taylor & Francis
Introduction: Polypharmacy, the use of multiple medications by one individual, is
increasingly common among older adults. Caring for the growing number of older people …

[HTML][HTML] Adverse outcomes of polypharmacy in older people: systematic review of reviews

LE Davies, G Spiers, A Kingston, A Todd… - Journal of the American …, 2020 - Elsevier
Objective Polypharmacy is widespread among older people, but the adverse outcomes
associated with it are unclear. We aim to synthesize current evidence on the adverse health …

Management of depression in older adults: a review

RM Kok, CF Reynolds - Jama, 2017 - jamanetwork.com
Importance Depression in older adults is a common psychiatric disorder affecting their
health-related quality of life. Major depression occurs in 2% of adults aged 55 years or older …

Sleep in the aging population

B Miner, MH Kryger - Sleep medicine clinics, 2020 - sleep.theclinics.com
Sleep is an important component for health and wellness across the lifespan. The number of
people in the United States who are 65 years or older is steadily increasing, and is expected …

Evidence on multimorbidity from definition to intervention: an overview of systematic reviews

X Xu, GD Mishra, M Jones - Ageing research reviews, 2017 - Elsevier
The increasing challenge of multiple chronic diseases (multimorbidity) requires more
evidence-based knowledge and effective practice. In order to better understand the existing …

Association between polypharmacy and death: a systematic review and meta-analysis

N Leelakanok, AL Holcombe, BC Lund, X Gu… - Journal of the American …, 2017 - Elsevier
Objective Polypharmacy has been linked to a myriad of adverse consequences, and
escalating rates of polypharmacy present an emerging concern, particularly among older …

Interventions to improve the appropriate use of polypharmacy for older people

A Rankin, CA Cadogan, SM Patterson… - Cochrane Database …, 2018 - cochranelibrary.com
Background Inappropriate polypharmacy is a particular concern in older people and is
associated with negative health outcomes. Choosing the best interventions to improve …

[HTML][HTML] Appropriate polypharmacy and medicine safety: when many is not too many

CA Cadogan, C Ryan, CM Hughes - Drug safety, 2016 - Springer
The use of multiple medicines (polypharmacy) is increasingly common in middle-aged and
older populations. Ensuring the correct balance between the prescribing of 'many'drugs and …