G protein-coupled receptors (GPCRs) are well-studied and the most traceable cell surface
receptors for drug discovery. One of the intriguing members of this family is G protein …

In our study, using chromatographic techniques, we isolated three bioactive compounds,
which were structurally elucidated as (E)-2-(3-(3, 4-dimethoxyphenyl) acrylamido)-N …

Colorectal cancer (CRC) is a prevalent and deadly disease, necessitating the exploration of
novel therapeutic strategies. Traditional chemotherapy often encounters drug resistance and …

Background The effects of gut microbiota and metabolites on the responses to immune
checkpoint inhibitors (ICIs) in advanced epidermal growth factor receptor (EGFR) wild-type …

Introduction The inhibition of melanoma adhesion through adhesion molecules, such as
integrins and E-cadherin, may represent a promising strategy for managing melanoma …

CTCE‐9908, a CXC chemokine receptor 4 (CXCR4) antagonist, prevents CXCR4
phosphorylation and inhibits the interaction with chemokine ligand 12 (CXCL12) and …

Melanoma is an aggressive malignancy and remains a major cause of skin cancer mortality,
highlighting the need for new treatment strategies. Recent findings revealed that l …

Melanoma, an aggressive malignancy derived from melanocytes, ranks among the most
highly metastatic forms of human cancer [1]. Although major advances have been made in …