The formation of adipocytes during embryogenesis has been largely understudied.
However, preadipocytes appear to originate from multipotent mesenchymal stromal/stem …

MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression and,
therefore, biological processes in different tissues. A major function of miRNAs in adipose …

The paternal heredity of obesity and diabetes induced by a high-fat and/or high-sugar diet
(Western-like diet) has been demonstrated through epidemiological analysis of human …

Senile osteoporosis has become a worldwide bone disease with the aging of the world
population. It increases the risk of bone fracture and seriously affects human health. Unlike …

In recent years, the link between regulatory microRNAs (miRNAs) and diseases has been
the object of intensive research. miRNAs have emerged as key mediators of metabolic …

One of the biggest challenges in the management of obesity is the prevention of weight
regain after successful weight loss. Weight regain after weight loss has large interindividual …

MicroRNAs (miRNAs) repress cellular protein levels to provide a sophisticated parameter of
gene regulation that coordinates a broad spectrum of biological processes. Bone …

Hyperlipidemia is a risk factor for various cardiovascular and metabolic disorders.
Overproduction of lipoproteins, a process that is dependent on microsomal triglyceride …

Adipogenesis, osteogenesis and chondrogenesis of human mesenchymal stem/stromal
cells (MSC) are complex and highly regulated processes. Over the years, several studies …

The therapeutic potential of mesenchymal stromal cells (MSCs) is evident by the number of
new and ongoing trials targeting an impressive variety of conditions. In bone and cartilage …