The incidence of inflammatory bowel disease (IBD) is rapidly rising throughout the world.
Although tremendous efforts have been made, limited therapeutics are available for IBD …

The regeneration of bone defects in patients with diabetes mellitus (DM) is remarkably
impaired by hyperglycemia and over-expressed proinflammatory cytokines, proteinases …

Nanoparticles are nanomaterials with three external nanoscale dimensions and an average
size ranging from 1 to 1000 nm. Nanoparticles have gained notoriety in technological …

Injectable hydrogels with the capability to cast a hypoxic microenvironment is of great
potentialities to develop novel therapies for tissue regeneration. However, the relative …

The nontargeted distribution and uncontrolled in vivo release of drugs impede their efficacy
in the treatment of rheumatoid arthritis (RA). Delivering drugs to arthritic joints and releasing …

Enzyme-responsive hydrogels, formed by step growth photopolymerization of biscysteine
peptide linkers with alkene functionalized polyethylene glycol, provide interesting …

Delivering the right drug (s) to the right place at the right time is part of a collection of
objectives that has long been a cornerstone of the nanomedicine field since its inception …

Despite numerous attempts to engineer cartilage tissue in recent years, significant
challenges remain regarding hyaline cartilage regeneration. One main reason is that the …

Alginate is a polysaccharide used extensively in biomedical applications due to its
biocompatibility and suitability for hydrogel fabrication using mild reaction chemistries …

ABSTRACT A large number of studies have manifested long non-coding RNA (lncRNA) is
involved in the modulation of the development of periodontitis, but the specific mechanism …