Reactive oxygen species and cancer paradox: to promote or to suppress?
Reactive oxygen species (ROS), a group of highly reactive ions and molecules, are
increasingly being appreciated as powerful signaling molecules involved in the regulation of …
increasingly being appreciated as powerful signaling molecules involved in the regulation of …
[HTML][HTML] Antioxidants as precision weapons in war against cancer chemotherapy induced toxicity–Exploring the armoury of obscurity
Cancer is the leading cause of mortality worldwide, accounting for almost 13% of deaths in
the world. Among the conventional cancer treatments, chemotherapy is most frequently …
the world. Among the conventional cancer treatments, chemotherapy is most frequently …
Redox regulation of cell survival
D Trachootham, W Lu, MA Ogasawara… - Antioxidants & redox …, 2008 - liebertpub.com
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) play important roles in
regulation of cell survival. In general, moderate levels of ROS/RNS may function as signals …
regulation of cell survival. In general, moderate levels of ROS/RNS may function as signals …
Chronic inflammation and cancer.
E Shacter, SA Weitzman - Oncology (Williston Park, NY), 2002 - europepmc.org
A substantial body of evidence supports the conclusion that chronic inflammation can
predispose an individual to cancer, as demonstrated by the association between chronic …
predispose an individual to cancer, as demonstrated by the association between chronic …
[HTML][HTML] Microalgal cell biofactory—therapeutic, nutraceutical and functional food applications
BR Kiran, S Venkata Mohan - Plants, 2021 - mdpi.com
Microalgae are multifaceted photosynthetic microorganisms with emerging business
potential. They are present ubiquitously in terrestrial and aquatic environments with rich …
potential. They are present ubiquitously in terrestrial and aquatic environments with rich …
Reactive oxygen species and angiogenesis: NADPH oxidase as target for cancer therapy
M Ushio-Fukai, Y Nakamura - Cancer letters, 2008 - Elsevier
Angiogenesis is essential for tumor growth, metastasis, arteriosclerosis as well as embryonic
development and wound healing. Its process is dependent on cell proliferation, migration …
development and wound healing. Its process is dependent on cell proliferation, migration …
The role of the cyclin-dependent kinase inhibitor p21 in apoptosis
Cancer develops when the balance between cell proliferation and cell death is disrupted,
and the ensuing aberrant proliferation leads to tumor growth. The cyclin-dependent kinase …
and the ensuing aberrant proliferation leads to tumor growth. The cyclin-dependent kinase …
Natural and synthetic antioxidants: an updated overview
The current understanding of the complex role of ROS in the organism and pathological
sequelae of oxidative stress points to the necessity of comprehensive studies of antioxidant …
sequelae of oxidative stress points to the necessity of comprehensive studies of antioxidant …
Transcriptional regulation of the p21 (WAF1/CIP1) gene
Cell cycle progression is controlled by the cyclindependent kinases (CDKs). CDKs are the
catalytic partners of the cyclins [reviewed in 1]. Regulators of G1 progression in mammalian …
catalytic partners of the cyclins [reviewed in 1]. Regulators of G1 progression in mammalian …
[HTML][HTML] Specific structural determinants are responsible for the antioxidant activity and the cell cycle effects of resveratrol
LA Stivala, M Savio, F Carafoli, P Perucca… - Journal of Biological …, 2001 - ASBMB
Resveratrol (3, 4′, 5-trihydroxy-trans-stilbene) is a natural phytoalexin found in grapes and
wine, which shows antioxidant and antiproliferative activities. In this study we have …
wine, which shows antioxidant and antiproliferative activities. In this study we have …