Arginine methylation next to the PY‐NLS modulates Transportin binding and nuclear import of FUS
D Dormann, T Madl, CF Valori, E Bentmann… - The EMBO …, 2012 - embopress.org
Fused in sarcoma (FUS) is a nuclear protein that carries a proline‐tyrosine nuclear
localization signal (PY‐NLS) and is imported into the nucleus via Transportin (TRN). Defects …
localization signal (PY‐NLS) and is imported into the nucleus via Transportin (TRN). Defects …
Chemical gene synthesis: strategies, softwares, error corrections, and applications
AS Xiong, RH Peng, J Zhuang, F Gao… - FEMS microbiology …, 2008 - academic.oup.com
Chemical synthesis of DNA sequences provides a powerful tool for modifying genes and for
studying gene structure, expression and function. Modified genes and consequently …
studying gene structure, expression and function. Modified genes and consequently …
Spanning high-dimensional expression space using ribosome-binding site combinatorics
L Zelcbuch, N Antonovsky, A Bar-Even… - Nucleic acids …, 2013 - academic.oup.com
Protein levels are a dominant factor shaping natural and synthetic biological systems.
Although proper functioning of metabolic pathways relies on precise control of enzyme …
Although proper functioning of metabolic pathways relies on precise control of enzyme …
Cryptic genetic variation promotes rapid evolutionary adaptation in an RNA enzyme
Cryptic variation is caused by the robustness of phenotypes to mutations. Cryptic variation
has no effect on phenotypes in a given genetic or environmental background, but it can have …
has no effect on phenotypes in a given genetic or environmental background, but it can have …
Ribosomal protein S25 dependency reveals a common mechanism for diverse internal ribosome entry sites and ribosome shunting
During viral infection or cellular stress, cap-dependent translation is shut down. Proteins that
are synthesized under these conditions use alternative mechanisms to initiate translation …
are synthesized under these conditions use alternative mechanisms to initiate translation …
Enzymatic synthesis of an ezetimibe intermediate using carbonyl reductase coupled with glucose dehydrogenase in an aqueous-organic solvent system
Abstract (4S)-3-[(5S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1, 3-oxazolidin-2-
one ((S)-ET-5) is an important chiral intermediate in the synthesis of chiral side chain of …
one ((S)-ET-5) is an important chiral intermediate in the synthesis of chiral side chain of …
Gene synthesis: methods and applications
DNA synthesis techniques and technologies are quickly becoming a cornerstone of modern
molecular biology and play a pivotal role in the field of synthetic biology. The ability to …
molecular biology and play a pivotal role in the field of synthetic biology. The ability to …
In vitro and in vivo model of a novel immunotherapy approach for chronic lymphocytic leukemia by anti-CD23 chimeric antigen receptor
GMP Giordano Attianese, V Marin… - Blood, The Journal …, 2011 - ashpublications.org
Chronic lymphocytic leukemia (CLL) is characterized by an accumulation of mature CD19+
CD5+ CD20dim B lymphocytes that typically express the B-cell activation marker CD23. In …
CD5+ CD20dim B lymphocytes that typically express the B-cell activation marker CD23. In …
Current challenges in nucleic acid synthesis
RI Hogrefe, B Midthune… - Israel Journal of Chemistry, 2013 - Wiley Online Library
Our understanding of the role of nucleic acids in regulating the process of life is growing
rapidly. As researchers delve deeper into the cellular activity of molecules such as …
rapidly. As researchers delve deeper into the cellular activity of molecules such as …
Two Distinctive POMC Promoters Modify Gene Expression in Cushing Disease
T Araki, Y Tone, M Yamamoto… - The Journal of …, 2021 - academic.oup.com
Context Mechanisms underlying pituitary corticotroph adenoma adrenocorticotropin (ACTH)
production are poorly understood, yet circulating ACTH levels closely correlate with …
production are poorly understood, yet circulating ACTH levels closely correlate with …