Metformin contamination in global waters: Biotic and abiotic transformation, byproduct generation and toxicity, and evaluation as a pharmaceutical indicator

Y He, Y Zhang, F Ju - Environmental Science & Technology, 2022 - ACS Publications
Metformin is the first-line antidiabetic drug and one of the most prescribed medications
worldwide. Because of its ubiquitous occurrence in global waters and demonstrated …

Metformin as an emerging concern in wastewater: Occurrence, analysis and treatment methods

A Balakrishnan, M Sillanpää, MM Jacob… - Environmental Research, 2022 - Elsevier
Metformin is a wonder drug used as an anti-hypoglycemic medication; it is also used as a
cancer suppression medicament. Metformin is a first line of drug choice used by doctors for …

The potential for adverse effects in fish exposed to antidepressants in the aquatic environment

SL Gould, MJ Winter, WHJ Norton… - … Science & Technology, 2021 - ACS Publications
Antidepressants are one of the most commonly prescribed pharmaceutical classes for the
treatment of psychiatric conditions. They act via modulation of brain monoaminergic …

Occurrence, toxic effects and removal of metformin in the aquatic environments in the world: Recent trends and perspectives

GA Elizalde-Velázquez, LM Gómez-Oliván - Science of The Total …, 2020 - Elsevier
Metformin (MET) is the most common drug used to treat type 2 diabetes, but also it is used
as an anticancer agent and as a treatment for polycystic ovary syndrome. This drug is not …

The assessment of environmental risk related to the occurrence of pharmaceuticals in bottom sediments of the Odra River estuary (SW Baltic Sea)

D Kucharski, G Nałęcz-Jawecki, P Drzewicz… - Science of The Total …, 2022 - Elsevier
The occurrence of 130 pharmaceutically active compounds (PhACs) in sediments collected
from 70 sampling sites in the Odra River estuary (SW Baltic Sea) was investigated. The …

[HTML][HTML] Fate, transport, and risk assessment of widely prescribed pharmaceuticals in terrestrial and aquatic systems: A review

JF Shaheen, B Sizirici, I Yildiz - Emerging Contaminants, 2022 - Elsevier
Rapid development of pharmaceuticals outpaces the efforts to regulate and monitor their
trace concentrations in the environment. This emerging issue can only be solved through …

Occurrence, sources and environmental risk assessment of pharmaceuticals in the Sea of Marmara, Turkey

NE Korkmaz, B Savun-Hekimoğlu, A Aksu… - Science of the Total …, 2022 - Elsevier
In the present study, the occurrence and spatial distribution of selected eleven
pharmaceuticals were investigated in the Sea of Marmara, Turkey. Samples were collected …

Oxidative stress as a potential mechanism by which guanylurea disrupts the embryogenesis of Danio rerio

GA Elizalde-Velázquez, LM Gómez-Oliván… - Science of the Total …, 2021 - Elsevier
Metformin is one the most prescribed drug to treat type 2 diabetes. In wastewater treatment
plants, this drug is bacterially transformed to guanylurea, which occurs at higher …

Sample preparation to determine pharmaceutical and personal care products in an all-water matrix: solid phase extraction

D Sadutto, Y Picó - Molecules, 2020 - mdpi.com
Pharmaceuticals and personal care products (PPCPs) are abundantly used by people, and
some of them are excreted unaltered or as metabolites through urine, with the sewage being …

A critical review of the current environmental risks posed by the antidiabetic Metformin and the status, advances, and trends in adsorption technologies for its …

Y Vieira, TH Ribeiro, J Leichtweis, GL Dotto… - Journal of Water …, 2023 - Elsevier
The consumption of the antidiabetic drug Metformin (MTFN) has escalated over the last
years due to the worrisome modern sedentary lifestyle. Since MTFN is not metabolized, it …