Bacteria, similar to most organisms, have a love–hate relationship with metals: a specific
metal may be essential for survival yet toxic in certain forms and concentrations. Metal ions …

The growing prevalence of antimicrobial drug resistance in pathogenic bacteria is a critical
threat to global health. Conventional antibiotics still play a crucial role in treating bacterial …

This review covers the main aspects concerning the chemistry, the biological activity and the
analytical determination of oxazolidinones, the only new class of synthetic antibiotics …

Conspectus This Account describes fundamental chemistry that promoted the discovery of
new antibiotics. Specifically, the NH acidity of simple hydroxamic acid derivatives facilitated …

Drug repurposing is considered a promising strategy to fight antimicrobial resistance (AMR).
Methotrexate (Mtx), a classical anticancer drug, could strongly inhibit bacterial dihydrofolate …

Antimicrobial resistance, caused by persistent adaptation and growing resistance of
pathogenic bacteria to overprescribed antibiotics, poses one of the most serious and urgent …

The increasing bacterial resistance caused by antibiotic overuse has promoted the search
for new antimicrobial strategies. Metals uptake via bacterial metallophores are studied to …

The emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) infections
is one of the most crucial challenges currently faced by the scientific community …

Antimicrobial resistance (AMR) is a global threat to society due to the increasing emergence
of multi-drug resistant bacteria that are not susceptible to our last line of defence antibiotics …

With the rising levels of drug resistance, developing efficient antimicrobial therapies has
become a priority. A promising strategy is the conjugation of antibiotics with relevant …