Cannabinoids in the modulation of oxidative signaling
Cannabis sativa-derived compounds, such as delta-9-tetrahydrocannabinol (THC) and
cannabidiol (CBD), and components of the endocannabinoids system, such as N …
cannabidiol (CBD), and components of the endocannabinoids system, such as N …
[HTML][HTML] TET protein inhibitors: Potential and limitations
R Kaplánek, Z Kejík, J Hajduch, K Veselá… - Biomedicine & …, 2023 - Elsevier
TET proteins (methylcytosine dioxygenases) play an important role in the regulation of gene
expression. Dysregulation of their activity is associated with many serious pathogenic states …
expression. Dysregulation of their activity is associated with many serious pathogenic states …
[HTML][HTML] LncRNA UCA1 promotes pancreatic cancer cell migration by regulating mitochondrial dynamics via the MAPK pathway
H Wang, Y Ding, Y He, Z Yu, Y Zhou, A Gong… - Archives of Biochemistry …, 2023 - Elsevier
Purpose Long non-coding RNA urothelial cancer associated 1 (UCA1) serves as an
oncogene in various cancers. However, the mechanism underlying the role of UCA1 in …
oncogene in various cancers. However, the mechanism underlying the role of UCA1 in …
Impairment of electron transport chain and induction of apoptosis by chrysin nanoparticles targeting succinate-ubiquinone oxidoreductase in pancreatic and lung …
Background Flavonoids may help ameliorate the incidence of the major causes of tumor-
related mortality, such as pancreatic ductal adenocarcinoma (PDAC) and lung cancer, which …
related mortality, such as pancreatic ductal adenocarcinoma (PDAC) and lung cancer, which …
Illuminating the immunological landscape: mitochondrial gene defects in pancreatic cancer through a multiomics lens
H Chi, L Su, Y Yan, X Gu, K Su, H Li, L Yu… - Frontiers in …, 2024 - frontiersin.org
This comprehensive review delves into the complex interplay between mitochondrial gene
defects and pancreatic cancer pathogenesis through a multiomics approach. By …
defects and pancreatic cancer pathogenesis through a multiomics approach. By …
UBXN1 promotes liver tumorigenesis by regulating mitochondrial homeostasis
K Jiao, G Xu, Y Liu, Z Yang, L Xiang, Z Chen… - Journal of Translational …, 2024 - Springer
Background The maintenance of mitochondrial homeostasis is critical for tumor initiation and
malignant progression because it increases tumor cell survival and growth. The molecular …
malignant progression because it increases tumor cell survival and growth. The molecular …
Cartilage Damage Pathological Characteristics of Diabetic Neuropathic Osteoarthropathy
PL Liu, JY Diao, Q Wang, H Liu, Y Zhang… - Analytical Cellular …, 2023 - Wiley Online Library
Background. Diabetic neuropathic osteoarthropathy (DNOAP) is a rare and easily missed
complication for diabetes that leads to increased morbidity and mortality. DNOAP is …
complication for diabetes that leads to increased morbidity and mortality. DNOAP is …
Exploration of anti‐leukemic effect of soft coral‐derived 13‐acetoxysarcocrassolide: Induction of apoptosis via oxidative stress as a potent inhibitor of heat shock …
HK Chin, MC Lu, KC Hsu, M El‐Shazly… - … Journal of Medical …, 2023 - Wiley Online Library
Acetoxysarcocrassolide (13‐AC) is a marine cembranoid derived from the aquaculture soft
coral of Lobophytum crassum. The cytotoxic effect of 13‐AC against leukemia cells was …
coral of Lobophytum crassum. The cytotoxic effect of 13‐AC against leukemia cells was …