Aging is characterized by loss of spinal motor neurons (MNs) due to apoptosis, reduced
insulin‐like growth factor I signaling, elevated amounts of circulating cytokines, and …

OBJECTIVES: This review aims to define the concept of neuromuscular fatigue and to
present the current knowledge of the central and peripheral factors at the origin of this …

Drawing on the disciplines of neurophysiology and physics, Neuromechanics of Human
Movement, Fourth Edition, explores how the nervous system controls the actions of muscles …

Insight into the magnitude of muscle forces is important in biomechanics research, for
example because muscle forces are the main determinants of joint loading. Unfortunately …

Movement is accomplished by the controlled activation of motor unit populations. Our
understanding of motor unit physiology has been derived from experimental work on the …

Soon after Edward Liddell [1895–1981] and Charles Sherrington [1857–1952] introduced
the concept of a motor unit in 1925 and the necessary technology was developed, the …

The purpose of this review was to examine three issues that limit our understanding of motor
unit physiology:(1) the range and distribution of the innervation ratios in a muscle;(2) the …

The aim of this study was to investigate the association between the rate of torque
development and maximal motor unit discharge frequency in young and elderly adults as …

This study employed longitudinal measures of evoked spinal reflex responses (Hoffman
reflex, V wave) to investigate changes in the activation of muscle and to determine if there …

It has long been believed that training for increased strength not only affects muscle tissue,
but also results in adaptive changes in the central nervous system. However, only in the last …