It has been more than two decades since aptamer and the systematic evolution of ligands by
exponential enrichment (SELEX) method were discovered by Larry Gold and Andrew …

Nucleic acid aptamers are single stranded DNA or RNA sequences that specifically bind a
cognate ligand. In addition to their widespread use as stand-alone affinity binding reagents …

Aptasensors have attracted considerable interest and widespread application in point-of-
care testing worldwide. One of the biggest challenges of a point-of-care (POC) is the …

Selected from random pools of DNA or RNA molecules through systematic evolution of
ligands by exponential enrichment (SELEX), aptamers can bind to target molecules with …

<? xm-replace_text {Heading}?> Abstract It has been 20 years since aptamer and SELEX
(systematic evolution of ligands by exponential enrichment) were described independently …

Abasic site (AP site) in the triplex structure can recognize specific target with high selectivity.
In this study, this character was first applied to develop a simple, sensitive, and selective …

The DNA aptamer for adenosine and ATP has been used as a model system for developing
analytical biosensors. For practical reasons, it is important to distinguish adenosine from …

DNA single-nucleotide polymorphism (SNP) detection has attracted much attention due to
mutation related diseases. Various methods for SNP detection have been proposed and …

In this study, a dual-emission fluorescence resonance energy transfer (FRET) polymeric
nanoprobe by single-wavelength excitation was developed for sensitive and selective …

DNA-based switches are structure-switching biomolecules widely employed in different
bioanalytical applications. Of particular interest are DNA–based switches whose activity is …