Raman spectroscopy for cancer detection and cancer surgery guidance: translation to the clinics

IP Santos, EM Barroso, TCB Schut, PJ Caspers… - Analyst, 2017 - pubs.rsc.org
Oncological applications of Raman spectroscopy have been contemplated, pursued, and
developed at academic level for at least 25 years. Published studies aim to detect pre …

Role of COX-2/PGE2 mediated inflammation in oral squamous cell carcinoma

WHS Nasry, JC Rodriguez-Lecompte, CK Martin - Cancers, 2018 - mdpi.com
A significant amount of research indicates that the cyclooxygenase/prostaglandin E2 (PGE2)
pathway of inflammation contributes to the development and progression of a variety of …

Mandibular reconstruction after cancer: an in-house approach to manufacturing cutting guides

R Bosc, B Hersant, R Carloni, J Niddam… - International journal of …, 2017 - Elsevier
The restoration of mandibular bone defects after cancer can be facilitated by computer-
assisted preoperative planning. The aim of this study was to assess an in-house …

Deep convolutional neural networks for tongue squamous cell carcinoma classification using Raman spectroscopy

M Yu, H Yan, J Xia, L Zhu, T Zhang, Z Zhu, X Lou… - Photodiagnosis and …, 2019 - Elsevier
With deep convolutional neural networks and fiber optic Raman spectroscopy, this study
presents a novel classification method that discriminates tongue squamous cell carcinoma …

Raman spectroscopy: A potential diagnostic tool for oral diseases

Y Zhang, L Ren, Q Wang, Z Wen, C Liu… - Frontiers in Cellular and …, 2022 - frontiersin.org
Oral diseases impose a major health burden worldwide and have a profound effect on
general health. Dental caries, periodontal diseases, and oral cancers are the most common …

Surgical margins in head and neck cancer: Intra-and postoperative considerations

KT Robbins, A Triantafyllou, C Suárez, F López… - Auris Nasus …, 2019 - Elsevier
Objective To provide a perspective on the significance of recent reports for optimizing cancer
free surgical margins that have challenged standard practices. Methods We conducted a …

Water concentration analysis by Raman spectroscopy to determine the location of the tumor border in oral cancer surgery

EM Barroso, RWH Smits, CGF van Lanschot… - Cancer research, 2016 - AACR
Adequate resection of oral cavity squamous cell carcinoma (OCSCC) means complete
tumor removal with a clear margin of more than 5 mm. For OCSCC, 85% of the surgical …

Margin analysis in head and neck cancer: state of the art and future directions

MM Li, SV Puram, DA Silverman, MO Old… - Annals of surgical …, 2019 - Springer
Background The status of surgical margins is the most important prognosticator for patients
undergoing surgical resection of head and neck squamous cell carcinoma (HNSCC) …

Assessment of the deep resection margin during oral cancer surgery: A systematic review

SGB de Koning, A Schaeffers, W Schats… - European Journal of …, 2021 - Elsevier
The main challenge for radical resection in oral cancer surgery is to obtain adequate
resection margins. Especially the deep margin, which can only be estimated based on …

Evaluation of the sensitivity of metabolic profiling by rapid evaporative ionization mass spectrometry: toward more radical oral cavity cancer resections

PM Vaysse, I Demers, MFCM van den Hout… - Analytical …, 2022 - ACS Publications
Radical resection for patients with oral cavity cancer remains challenging. Rapid
evaporative ionization mass spectrometry (REIMS) of electrosurgical vapors has been …