Handbook of pharmaceutical granulation technology

DM Parikh - Drugs and the pharmaceutical sciences, 2005 - api.taylorfrancis.com
Since the Handbook of Pharmaceutical Granulation Technology, first and second editions,
were published, there have been rapid developments in the science of granulation, particle …

Metamorphosis of twin screw extruder-based granulation technology: Applications focusing on its impact on conventional granulation technology

RR Rao, A Pandey, AR Hegde, VI Kulkarni… - AAPS …, 2022 - Springer
In order to be at pace with the market requirements of solid dosage forms and regulatory
standards, a transformation towards systematic processing using continuous manufacturing …

Multi-objective optimization of high-shear wet granulation process for better granule properties and fluidized bed drying characteristics

VV Kenekar, SB Ghugare, V Patil-Shinde - Powder Technology, 2023 - Elsevier
This study determines the effects of influential process parameters of high-shear wet
granulation (HSWG) on the critical process and quality attributes of the granules. The wet …

Effect of Manufacturing Conditions on Particle Characteristics in the Drug-Layering Process of a Novel Melt Granulation Technology, MALCORE®, Using a Design of …

N Yoshihara, R Kimata, T Terukina, H Kondo - Journal of Pharmaceutical …, 2023 - Springer
Purpose MALCORE®, a manufacturing technology of drug-containing particles (DCPs) for
coating, consists of a 2-step melt granulation process. The drug-layering process in the …

Continuous granulation

C Vervaet, JP Remon - Handbook of pharmaceutical granulation …, 2016 - taylorfrancis.com
INTRODUCTION: CONTINUOUS PROCESSING OF SOLID DOSAGE FORMS For decades,
the manufacturing of solid dosage forms in the pharmaceutical industry has been …

[HTML][HTML] Effects of the controlled temperature in the production of high-shear granulated protein-containing granules

K Kristó, E Csík, D Sebők, Á Kukovecz, T Sovány… - Powder Technology, 2022 - Elsevier
During wet granulation, the sample can be exposed to considerable mechanical effects,
moisture content and elevated temperatures, and during high-shear granulation the impeller …

A new methodology of understanding the mechanism of high shear wet granulation based on experiment and molecular dynamics simulation

K Zhou, Z Liu, R Fan, M Zhao, L Luo, Y Wang… - International Journal of …, 2023 - Elsevier
In high shear wet granulation (HSWG), the interaction mechanism between binder and
powder with different sugar content is still unclear. Herein, the law and mechanism of the …

D11 型双螺杆高剪切湿法制粒机制粒性能模拟与评价

胡安, 毛元瑞, 周国发 - 中国塑料, 2024 - plaschina.com.cn
基于双螺杆高剪切湿法制粒工艺与装备协同集成数字化虚拟样机仿真方法, 模拟评价了D11
小型双螺杆高剪切湿法制粒机的结构特征与螺杆尺度对制粒性能和关键质量属性的影响 …

Mixing of powders under periodic shear stress: effect of initial filling level

LG Obregón-Quiñones… - EUREKA: Physics …, 2023 - journal.eu-jr.eu
Powder Mixing continues being of great importance in the field of particle technology
because of the challenge to get homogeneous mixtures at a large scale. However, it is still …

[HTML][HTML] Design of calcium hydroxide–based granules for livestock sanitation

S Yamanaka, S Hirano, K Uwai, K Tokuraku - Case Studies in Chemical …, 2020 - Elsevier
Calcium hydroxide has the potential to be an effective disinfectant against viruses and
pathogenic bacteria due to its strong alkalinity. Herein we report user-friendly calcium …