Neurovascular coupling: motive unknown

PJ Drew - Trends in neurosciences, 2022 - cell.com
In the brain, increases in neural activity drive changes in local blood flow via neurovascular
coupling. The common explanation for increased blood flow (known as functional …

Ultra-slow oscillations in fMRI and resting-state connectivity: neuronal and vascular contributions and technical confounds

PJ Drew, C Mateo, KL Turner, X Yu, D Kleinfeld - Neuron, 2020 - cell.com
Summary Ultra-slow,∼ 0.1-Hz variations in the oxygenation level of brain blood are widely
used as an fMRI-based surrogate of" resting-state" neuronal activity. The temporal …

Neurovascular coupling and bilateral connectivity during NREM and REM sleep

KL Turner, KW Gheres, EA Proctor, PJ Drew - elife, 2020 - elifesciences.org
To understand how arousal state impacts cerebral hemodynamics and neurovascular
coupling, we monitored neural activity, behavior, and hemodynamic signals in un …

[HTML][HTML] rsHRF: A toolbox for resting-state HRF estimation and deconvolution

GR Wu, N Colenbier, S Van Den Bossche, K Clauw… - NeuroImage, 2021 - Elsevier
The hemodynamic response function (HRF) greatly influences the intra-and inter-subject
variability of brain activation and connectivity, and might confound the estimation of temporal …

nNOS-expressing interneurons control basal and behaviorally evoked arterial dilation in somatosensory cortex of mice

CT Echagarruga, KW Gheres, JN Norwood, PJ Drew - Elife, 2020 - elifesciences.org
Cortical neural activity is coupled to local arterial diameter and blood flow. However, which
neurons control the dynamics of cerebral arteries is not well understood. We dissected the …

Rude mechanicals in brain haemodynamics: non-neural actors that influence blood flow

A Das, K Murphy, PJ Drew - … Transactions of the Royal …, 2021 - royalsocietypublishing.org
Fluctuations in blood oxygenation and flow are widely used to infer brain activity during
resting-state functional magnetic resonance imaging (fMRI). However, there are strong …

Relating pupil diameter and blinking to cortical activity and hemodynamics across arousal states

KL Turner, KW Gheres, PJ Drew - Journal of Neuroscience, 2023 - Soc Neuroscience
Arousal state affects neural activity and vascular dynamics in the cortex, with sleep
associated with large changes in the local field potential and increases in cortical blood flow …

Photoacoustic imaging for microcirculation

S Mirg, KL Turner, H Chen, PJ Drew… - …, 2022 - Wiley Online Library
Microcirculation facilitates the blood‐tissue exchange of nutrients and regulates blood
perfusion. It is, therefore, essential in maintaining tissue health. Aberrations in …

Adaptive modulation of brain hemodynamics across stereotyped running episodes

A Bergel, E Tiran, T Deffieux, C Demené… - Nature …, 2020 - nature.com
During locomotion, theta and gamma rhythms are essential to ensure timely communication
between brain structures. However, their metabolic cost and contribution to neuroimaging …

Origins of 1/f-like tissue oxygenation fluctuations in the murine cortex

Q Zhang, KW Gheres, PJ Drew - PLoS biology, 2021 - journals.plos.org
The concentration of oxygen in the brain spontaneously fluctuates, and the distribution of
power in these fluctuations has a 1/f-like spectra, where the power present at low …