Immunological processes driving IgE sensitisation and disease development in males and females

J Leffler, PA Stumbles, DH Strickland - International Journal of Molecular …, 2018 - mdpi.com
IgE sensitisation has increased significantly over the last decades and is a crucial factor in
the development of allergic diseases. IgE antibodies are produced by B cells through the …

Targeting glycolysis in Th2 cells by pterostilbene attenuates clinical severities in an asthmatic mouse model and IL‐4 production in peripheral blood from asthmatic …

CT Liu, YC Song, TC Wu, KC Shiung, IH Chen… - …, 2022 - Wiley Online Library
Asthma, a major non‐communicable disease, affects both adults and children and is
associated with high morbidity compared with other chronic diseases. The glycolysis …

Lung responses in murine models of experimental asthma: value of house dust mite over ovalbumin sensitization

C Doras, F Petak, S Bayat, A Baudat… - Respiratory physiology …, 2018 - Elsevier
Ovalbumin (OVA) sensitization has limitations in modelling asthma. Thus, we examined the
value of allergic sensitization using a purified natural allergen, house dust mite (HDM), over …

The comparation of intraperitoneal injection and nasal-only delivery allergic rhinitis model challenged with different allergen concentration

Y Wang, Y Zhou, Y Zhu, W Yu, J Wang… - American Journal of …, 2019 - journals.sagepub.com
Background Predominantly, 2 animal models are used for allergic rhinitis (AR), which are
established by intraperitoneal (IP) injection plus local challenge and nasal-only delivery …

[HTML][HTML] 色氨酸代谢物调控Th17/Treg 分化在小鼠哮喘变应原特异性免疫治疗中的作用及机制研究

范文婷, 钟世民, 胡琦, 曾靖, 廖伟, 汪金玉 - 2018 - aammt.tmmu.edu.cn
目的对色氨酸代谢物调控Th17/Treg 分化在小鼠哮喘变应原特异性免疫治疗中的作用及机制
进行研究. 方法将30 只BALB/c 鼠随机法分为5 组: 对照组, 哮喘组, OVA-SIT 组(OVA …

Funny Channel Signaling in Equine Airway Disease

C Hunter - 2018 - scholarsjunction.msstate.edu
Traditional animal models of severe asthma do not recapitulate defining asthma
characteristics, including persistent airway hyper-responsiveness, and chronic neutrophilic …