Multifunctional histone variants in genome function
LH Wong, DJ Tremethick - Nature Reviews Genetics, 2024 - nature.com
Histones are integral components of eukaryotic chromatin that have a pivotal role in the
organization and function of the genome. The dynamic regulation of chromatin involves the …
organization and function of the genome. The dynamic regulation of chromatin involves the …
Determinants of Chromatin Organization in Aging and Cancer—Emerging Opportunities for Epigenetic Therapies and AI Technology
RM Castilho, LS Castilho, BH Palomares, CH Squarize - Genes, 2024 - mdpi.com
This review article critically examines the pivotal role of chromatin organization in gene
regulation, cellular differentiation, disease progression and aging. It explores the dynamic …
regulation, cellular differentiation, disease progression and aging. It explores the dynamic …
Keeping a Genomic Jungle in Check; How Eukaryotic Cells Regulate the Positive Feedback of Heterochromatin Expansion
BJ Korte - 2024 - studenttheses.uu.nl
Eukaryotic genomes contain many repetitive sequences that, without constant repression,
can induce genomic instability via rogue transcription, recombination, and transposition …
can induce genomic instability via rogue transcription, recombination, and transposition …