The utility and necessity of pretreatment with intravenous thrombolysis (IVT) before
mechanical thrombectomy (MT) remains an issue of strong debate. This study aims to …

Purpose To provide an update about the rapidly developing changes in the critical care
management of acute ischaemic stroke patients. Methods A narrative review was conducted …

Importance Whether intravenous thrombolysis is needed in combination with mechanical
thrombectomy in patients with acute large vessel occlusion stroke is unclear. Objective To …

Background In acute ischemic stroke, there is uncertainty regarding the benefit and risk of
administering intravenous alteplase before endovascular thrombectomy. Methods We …

Background Mechanical thrombectomy (MT) has become the cornerstone of acute ischemic
stroke management in patients with large vessel occlusion (LVO). Objective To assist …

Objective The substantial clinical improvement in acute ischemic stroke (AIS) patients
treated with mechanical thrombectomy (MT), combined with the poor response of proximal …

Background Direct mechanical thrombectomy may result in similar outcomes compared to a
bridging approach with intravenous thrombolysis (IVT+ MT) in acute ischemic stroke. Recent …

Background and Objectives Current guidelines recommend the use of mechanical
thrombectomy (MT) plus IV thrombolysis (aka bridging therapy [BT]) for patients with anterior …

Rationale Whether treatment with intravenous alteplase prior to mechanical thrombectomy
(MT) in acute ischemic stroke patients with large vessel occlusion is beneficial remains …

Background Whether intravenous thrombolysis before mechanical thrombectomy provides
additional benefit for functional outcome in acute ischemic stroke remains uncertain. We …