Biological functions of mesenchymal stem cells and clinical implications
Mesenchymal stem cells (MSCs) are isolated from multiple biological tissues—adult bone
marrow and adipose tissues and neonatal tissues such as umbilical cord and placenta. In …
marrow and adipose tissues and neonatal tissues such as umbilical cord and placenta. In …
Mesenchymal stem cells and immunomodulation: current status and future prospects
F Gao, SM Chiu, DAL Motan, Z Zhang, L Chen… - Cell death & …, 2016 - nature.com
The unique immunomodulatory properties of mesenchymal stem cells (MSCs) make them
an invaluable cell type for the repair of tissue/organ damage caused by chronic inflammation …
an invaluable cell type for the repair of tissue/organ damage caused by chronic inflammation …
Mesenchymal stem cells are short-lived and do not migrate beyond the lungs after intravenous infusion
E Eggenhofer, V Benseler, A Kroemer… - Frontiers in …, 2012 - frontiersin.org
Mesenchymal stem cells (MSC) are under investigation as a therapy for a variety of
disorders. Although animal models show long term regenerative and immunomodulatory …
disorders. Although animal models show long term regenerative and immunomodulatory …
Immunoregulation by mesenchymal stem cells: biological aspects and clinical applications
ME Castro-Manrreza… - Journal of immunology …, 2015 - Wiley Online Library
Mesenchymal stem cells (MSCs) are multipotent cells capable of differentiation into
mesenchymal lineages and that can be isolated from various tissues and easily cultivated in …
mesenchymal lineages and that can be isolated from various tissues and easily cultivated in …
Mesenchymal stem cells deliver exogenous microRNA-let7c via exosomes to attenuate renal fibrosis
The advancement of microRNA (miRNA) therapies has been hampered by difficulties in
delivering miRNA to the injured kidney in a robust and sustainable manner. Using …
delivering miRNA to the injured kidney in a robust and sustainable manner. Using …
Mesenchymal stem cells generate a CD4+CD25+Foxp3+ regulatory T cell population during the differentiation process of Th1 and Th17 cells
P Luz-Crawford, M Kurte, J Bravo-Alegría… - Stem cell research & …, 2013 - Springer
Abstract Introduction Mesenchymal stem cells (MSCs) are adult, multipotent, stem cells with
immunomodulatory properties. The mechanisms involved in the capacity of MSCs to inhibit …
immunomodulatory properties. The mechanisms involved in the capacity of MSCs to inhibit …
Mesenchymal stem or stromal cells: a review of clinical applications and manufacturing practices
Mesenchymal stem cells (MSC s) have recently generated great interest in the fields of
regenerative medicine and immunotherapy due to their unique biologic properties. In this …
regenerative medicine and immunotherapy due to their unique biologic properties. In this …
Advances in mesenchymal stem cell therapy for immune and inflammatory diseases: Use of cell-free products and human pluripotent stem cell-derived mesenchymal …
LT Wang, KJ Liu, HK Sytwu, ML Yen… - Stem cells translational …, 2021 - academic.oup.com
Mesenchymal stem cell therapy (MSCT) for immune and inflammatory diseases continues to
be popular based on progressive accumulation of preclinical mechanistic evidence. This …
be popular based on progressive accumulation of preclinical mechanistic evidence. This …
[HTML][HTML] Mesenchymal stromal cell exosome–enhanced regulatory T-cell production through an antigen-presenting cell–mediated pathway
Background aims The immunomodulatory property of mesenchymal stromal cell (MSC)
exosomes is well documented. On the basis of our previous report that MSC exosomes …
exosomes is well documented. On the basis of our previous report that MSC exosomes …
Autologous bone marrow-derived mesenchymal stromal cells for the treatment of allograft rejection after renal transplantation: results of a phase I study
MEJ Reinders, JW de Fijter, H Roelofs… - Stem cells …, 2013 - academic.oup.com
Despite excellent short-term results, long-term survival of transplanted kidneys has not
improved accordingly. Although alloimmune responses and calcineurin inhibitor-related …
improved accordingly. Although alloimmune responses and calcineurin inhibitor-related …