In recent years, animal models in psychiatric research have been criticized for their limited
translational value to the clinical situation. Failures in clinical trials have thus often been …

Alcohol consumption is an integral part of daily life in many societies. The benefits
associated with the production, sale, and use of alcoholic beverages come at an enormous …

The role of withdrawal‐related phenomena in the development and maintenance of alcohol
addiction remains under debate. A 'self‐medication'framework postulates that emotional …

Throughout the world, ethanol is both an important commercial commodity and a source of
major medical and social problems. Ethanol readily passes through biological membranes …

Binge drinking is prevalent and has serious biomedical consequences. In children,
adolescents, and young adults, it is a prominent risk factor for later development of alcohol …

The purpose of this review is to present animal research models that can be used to screen
and/or repurpose medications for the treatment of alcohol abuse and dependence. The …

Oscillatory brain activities support many physiological functions from motor control to
cognition. Disruptions of the normal oscillatory brain activities are commonly observed in …

The purpose of this review paper is to present evidence that rat animal models of alcoholism
provide an ideal platform for developing and screening medications that target alcohol …

Risk for alcohol dependence in humans has substantial genetic contributions. Successful
rodent models generally attempt to address only selected features of the human diagnosis …

Background: While the molecular entity responsible for the rewarding effects of virtually all
drugs of abuse is known, that for ethanol remains uncertain. Some lines of evidence suggest …