Inflammation and post‐traumatic stress disorder

H Hori, Y Kim - Psychiatry and clinical neurosciences, 2019 - Wiley Online Library
While post‐traumatic stress disorder (PTSD) is currently diagnosed based solely on classic
psychological and behavioral symptoms, a growing body of evidence has highlighted a link …

Dementia and cognitive impairment: epidemiology, diagnosis, and treatment

J Hugo, M Ganguli - Clinics in geriatric medicine, 2014 - geriatric.theclinics.com
When elderly patients and their families report symptoms of memory loss, experienced
clinicians know that these concerns refer to a range of cognitive abilities or to general …

Association of race and ethnicity with incidence of dementia among older adults

E Kornblith, A Bahorik, WJ Boscardin, F Xia, DE Barnes… - JAMA, 2022 - jamanetwork.com
Importance The racial and ethnic diversity of the US, including among patients receiving
their care at the Veterans Health Administration (VHA), is increasing. Dementia is a …

[HTML][HTML] International meta-analysis of PTSD genome-wide association studies identifies sex-and ancestry-specific genetic risk loci

CM Nievergelt, AX Maihofer, T Klengel… - Nature …, 2019 - nature.com
The risk of posttraumatic stress disorder (PTSD) following trauma is heritable, but robust
common variants have yet to be identified. In a multi-ethnic cohort including over 30,000 …

Plasma phospholipids identify antecedent memory impairment in older adults

M Mapstone, AK Cheema, MS Fiandaca, X Zhong… - Nature medicine, 2014 - nature.com
Alzheimer's disease causes a progressive dementia that currently affects over 35 million
individuals worldwide and is expected to affect 115 million by 2050 (ref. 1). There are no …

[HTML][HTML] Microglia, lifestyle stress, and neurodegeneration

C Madore, Z Yin, J Leibowitz, O Butovsky - Immunity, 2020 - cell.com
Recent years have witnessed a revolution in our understanding of microglia biology,
including their major role in the etiology and pathogenesis of neurodegenerative diseases …

Sleep: a novel mechanistic pathway, biomarker, and treatment target in the pathology of Alzheimer's disease?

BA Mander, JR Winer, WJ Jagust, MP Walker - Trends in neurosciences, 2016 - cell.com
Sleep disruption appears to be a core component of Alzheimer's disease (AD) and its
pathophysiology. Signature abnormalities of sleep emerge before clinical onset of AD …

[HTML][HTML] A systems approach to stress, stressors and resilience in humans

BS Oken, I Chamine, W Wakeland - Behavioural brain research, 2015 - Elsevier
The paper focuses on the biology of stress and resilience and their biomarkers in humans
from the system science perspective. A stressor pushes the physiological system away from …

Oxidative stress, inflammation, and neuroprogression in chronic PTSD

MW Miller, AP Lin, EJ Wolf… - Harvard review of …, 2018 - journals.lww.com
Posttraumatic stress disorder is a serious and often disabling syndrome that develops in
response to a traumatic event. Many individuals who initially develop the disorder go on to …

[HTML][HTML] The relationship between stress and Alzheimer's disease

NJ Justice - Neurobiology of stress, 2018 - Elsevier
Stress is critically involved in the development and progression of disease. From the stress
of undergoing treatments to facing your own mortality, the physiological processes that …