The current literature provides a body of evidence on C-Reactive Protein (CRP) and its
potential role in inflammation. However, most pieces of evidence are sparse and …

Sickle cell disease is an autosomal recessive disorder of the beta-globin gene, with resultant
deformation of the red blood cells and variable clinical outcomes. Nigeria is recognised as …

Sickle cell disease (SCD) is a major public health burden worldwide with increasing
morbidity and mortality. The study evaluates the risk factors associated with mortality in SCD …

Folic acid (FA) supplementation in sickle cell disease (SCD) patients lead to accumulation of
unmetabolized folic acid (UMFA) which might influence the level of cytokines and NK cell …

It is known that an inherited blood condition called sickle cell disease (SCD) is a result of
one gene. A number of blood and urine biomarkers have been determined in association …

Sickle cell disease (SCD) is an inherited disorder and a major health challenge in Nigeria.
Micronutrient deficiencies often associated with the disorder may cause inflammation and …

Objectives The impacts of stress on inflammation, although hypothesized, have not been
thoroughly examined, especially in relation to social and environmental factors and …

Introduction Acute pain episodes, also known as vaso-occlusive crises (VOC), are a major
symptom of sickle cell disease (SCD) and lead to frequent hospitalizations. The diagnosis of …

Background: Micronutrient deficiency is recognized in sickle cell anaemia (SCA) but it is not
known for certain whether changes in zinc, copper and copper-to-zinc ratio are associated …

Background: Hemoglobin polymerization in sickle cell anemia (SCA) leads to abnormally
rigid and adhesive erythrocytes that obstruct blood vessels, leading to poor tissue perfusion …