The role of the host—Neutrophil biology

ILC Chapple, J Hirschfeld, A Kantarci… - Periodontology …, 2023 - Wiley Online Library
Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with
lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial …

JNK pathway in CNS pathologies

T de los Reyes Corrales, M Losada-Pérez… - International journal of …, 2021 - mdpi.com
The c-Jun N-terminal kinase (JNK) signalling pathway is a conserved response to a wide
range of internal and external cellular stress signals. Beside the stress response, the JNK …

Sequential release of small extracellular vesicles from bilayered thiolated alginate/polyethylene glycol diacrylate hydrogels for scarless wound healing

Y Shen, G Xu, H Huang, K Wang, H Wang, M Lang… - ACS …, 2021 - ACS Publications
Excessive scar formation has adverse physiological and psychological effects on patients;
therefore, a therapeutic strategy for rapid wound healing and reduced scar formation is …

Rational selection of bioactive principles for wound healing applications: Growth factors and antioxidants

P Viaña‐Mendieta, ML Sánchez… - International wound …, 2022 - Wiley Online Library
Wound healing is a complex process of communication between growth factors, reactive
species of oxygen, cells, signalling pathways, and cytokines in the extracellular matrix, in …

Photopolymerized silk fibroin gel for advanced burn wound care

S Indrakumar, A Joshi, TK Dash, V Mishra… - International Journal of …, 2023 - Elsevier
The future of burn wound treatment lies in developing bioactive dressings for faster and
more effective healing and regeneration. Silk fibroin (SF) hydrogels have proven …

Periodontal ligament stem cells promote polarization of M2 macrophages

J Liu, H Wang, L Zhang, X Li, X Ding… - Journal of Leukocyte …, 2022 - academic.oup.com
Macrophages are widely distributed in a variety of tissues, and the different state of
macrophages polarization is closely related to the occurrence, development, and prognosis …

Comprehensive review of hybrid collagen and silk fibroin for cutaneous wound healing

R Naomi, J Ratanavaraporn, MB Fauzi - Materials, 2020 - mdpi.com
The use of hybridisation strategy in biomaterials technology provides a powerful synergistic
effect as a functional matrix. Silk fibroin (SF) has been widely used for drug delivery, and …

Oxidative stress and redox-dependent signaling in prostate cancer

EV Kalinina, LA Gavriliuk, VS Pokrovsky - Biochemistry (Moscow), 2022 - Springer
Tumor emergence and progression is complicated by the dual role of reactive oxygen
species (ROS). Low concentrations of ROS are essential for many intracellular metabolic …

[Retracted] Fibroblasts in Scar Formation: Biology and Clinical Translation

H Qian, Y Shan, R Gong, D Lin, M Zhang… - Oxidative Medicine …, 2022 - Wiley Online Library
Scarring, which develops due to fibroblast activation and excessive extracellular matrix
deposition, can cause physical, psychological, and cosmetic problems. Fibroblasts are the …

Therapeutic effects of tryptanthrin and tryptanthrin-6-oxime in models of rheumatoid arthritis

LN Kirpotina, IA Schepetkin, D Hammaker… - Frontiers in …, 2020 - frontiersin.org
Rheumatoid arthritis (RA) is a chronic autoimmune disease involving joint and bone
damage that is mediated in part by proteases and cytokines produced by synovial …