[HTML][HTML] Spaceflight associated neuro-ocular syndrome (SANS) and the neuro-ophthalmologic effects of microgravity: a review and an update

AG Lee, TH Mader, CR Gibson, W Tarver, P Rabiei… - npj …, 2020 - nature.com
Prolonged microgravity exposure during long-duration spaceflight (LDSF) produces unusual
physiologic and pathologic neuro-ophthalmic findings in astronauts. These microgravity …

Spaceflight-induced intracranial hypertension and visual impairment: pathophysiology and countermeasures

LF Zhang, AR Hargens - Physiological reviews, 2018 - journals.physiology.org
Visual impairment intracranial pressure (VIIP) syndrome is considered an unexplained
major risk for future long-duration spaceflight. NASA recently redefined this syndrome as …

Optic disc edema, globe flattening, choroidal folds, and hyperopic shifts observed in astronauts after long-duration space flight

TH Mader, CR Gibson, AF Pass, LA Kramer, AG Lee… - Ophthalmology, 2011 - Elsevier
PURPOSE: To describe the history, clinical findings, and possible etiologies of ophthalmic
findings discovered in 7 astronauts after long-duration space flight, and document vision …

Space flight-associated neuro-ocular syndrome (SANS)

AG Lee, TH Mader, CR Gibson, TJ Brunstetter… - Eye, 2018 - nature.com
Interesting novel and somewhat perplexing physiologic and pathologic neuro-ocular
findings have been documented in astronauts during and after long duration space flight …

[HTML][HTML] Microgravity-induced fluid shift and ophthalmic changes

ES Nelson, L Mulugeta, JG Myers - Life, 2014 - mdpi.com
Although changes to visual acuity in spaceflight have been observed in some astronauts
since the early days of the space program, the impact to the crew was considered minor …

Analogs of microgravity: head-down tilt and water immersion

DE Watenpaugh - Journal of Applied Physiology, 2016 - journals.physiology.org
This article briefly reviews the fidelity of ground-based methods used to simulate human
existence in weightlessness (spaceflight). These methods include horizontal bed rest (BR) …

Space flight–associated neuro-ocular syndrome

AG Lee, TH Mader, CR Gibson, W Tarver - JAMA ophthalmology, 2017 - jamanetwork.com
New and unique physiologic and pathologic systemic and neuro-ocular responses have
been documented in astronauts during and after long-duration space flight. Although the …

[HTML][HTML] Vascular and microvascular dysfunction induced by microgravity and its analogs in humans: mechanisms and countermeasures

N Navasiolava, M Yuan, R Murphy, A Robin… - Frontiers in …, 2020 - frontiersin.org
Weightlessness and physical inactivity have deleterious cardiovascular effects. The space
environment and its ground-based models offer conditions to study the cardiovascular …

[HTML][HTML] Implementation of exercise countermeasures during spaceflight and microgravity analogue studies: developing countermeasure protocols for bedrest in older …

ET Hedge, CA Patterson, CJ Mastrandrea… - Frontiers in …, 2022 - frontiersin.org
Significant progress has been made in the development of countermeasures to attenuate
the negative consequences of prolonged exposure to microgravity on astronauts' bodies …

Impairment of cerebral blood flow regulation in astronauts with orthostatic intolerance after flight

AP Blaber, N Goswami, RL Bondar, MS Kassam - Stroke, 2011 - Am Heart Assoc
Background and Purpose—We investigated cerebral blood flow regulation in astronauts
before and after flights. We hypothesized that autoregulation would be different before flight …