A cell's behavior is a consequence of the complex interactions between its numerous
constituents, such as DNA, RNA, proteins and small molecules. Cells use signaling …

The availability and utility of genome‐scale metabolic reconstructions have exploded since
the first genome‐scale reconstruction was published a decade ago. Reconstructions have …

The Handbook of Linear Algebra provides comprehensive coverage of linear algebra
concepts, applications, and computational software packages in an easy-to-use handbook …

Living things are unimaginably complex, yet they have withstood a withering assault of
harmful influences over several billion years. These influences include cataclysmic changes …

Microbial cells operate under governing constraints that limit their range of possible
functions. With the availability of annotated genome sequences, it has become possible to …

Genome sequences are now available that enable us to determine the biological
components that make up a cell or an organism. The discipline of systems biology examines …

Analysis of biological networks ANALYSIS OF BIOLOGICAL NETWORKS Page 2
ANALYSIS OF BIOLOGICAL NETWORKS EDITED BY BJO RN H. JUNKER and FALK …

This year marks the 25th anniversary of the coinage of the term metabolome [SG Oliver et
al., Trends Biotech. 16, 373–378 (1998)]. As the field rapidly advances, it is important to take …

Network-based definitions of biochemical pathways have emerged in recent years. These
pathway definitions insist on the balanced use of a whole network of biochemical reactions …

Elementary mode analysis is a useful metabolic pathway analysis tool to identify the
structure of a metabolic network that links the cellular phenotype to the corresponding …