[HTML][HTML] Moderate aerobic training inhibits middle-aged induced cardiac calcineurin-NFAT signaling by improving TGF-ß, NPR-A, SERCA2, and TRPC6 in Wistar rats
B Baghaiee, R Bayatmakoo, P Karimi… - Cell Journal …, 2021 - ncbi.nlm.nih.gov
Objective The purpose of this study was to investigate the effect of moderate-intensity
training on the calcineurin/nuclear factor of activated t-cells (NFAT) pathway and factors …
training on the calcineurin/nuclear factor of activated t-cells (NFAT) pathway and factors …
[HTML][HTML] Berberine exerts protective effects on cardiac senescence by regulating the Klotho/SIRT1 signaling pathway
C Li, S Jiang, H Wang, Y Wang, Y Han… - Biomedicine & …, 2022 - Elsevier
Berberine (BBR), an isoquinoline alkaloid, exerts protective effects on various cardiac
injuries, and also extends the lifespan of individuals. However, the cardioprotective effect of …
injuries, and also extends the lifespan of individuals. However, the cardioprotective effect of …
Skeletal Muscle Injury in Chronic Kidney Disease—From Histologic Changes to Molecular Mechanisms and to Novel Therapies
Chronic kidney disease (CKD) is associated with significant reductions in lean body mass
and in the mass of various tissues, including skeletal muscle, which causes fatigue and …
and in the mass of various tissues, including skeletal muscle, which causes fatigue and …
Involvement of sirtuins and klotho in cardioprotective effects of exercise training against waterpipe tobacco smoking-induced heart dysfunction
Despite its negative effect on the cardiovascular system, waterpipe smoking (WPS) is
currently popular worldwide, especially among youth. This study investigated the effects of …
currently popular worldwide, especially among youth. This study investigated the effects of …
[HTML][HTML] The high-intensity interval training mitigates the cardiac remodeling in spontaneously hypertensive rats
LE Engel, FLA de Souza, IC Giometti, K Okoshi… - Life Sciences, 2022 - Elsevier
Aim To evaluate the influence of high-intensity interval training (HIIT) on cardiac structural
and functional characteristics and myocardial mitogen-activated protein kinase (MAPK) …
and functional characteristics and myocardial mitogen-activated protein kinase (MAPK) …
Novel prevention insights into depletion of oxidative stress status through regular exercise and grape seed effective substance in heart ischemia rat model
Myocardial ischemia (MI) is recognized as the most frequent cardiovascular disease which
is the dominant cause of global morbidity and mortality. Artificial intelligence tools and …
is the dominant cause of global morbidity and mortality. Artificial intelligence tools and …
[HTML][HTML] The protective effect of Apelin-13 against cardiac hypertrophy through activating the PI3K-AKT-mTOR signaling pathway
Y Peng, R Jingming, C Shaowen, H Feng… - Iranian Journal of …, 2023 - ncbi.nlm.nih.gov
Objective (s): To determine the protective effect of Apelin-13 on cardiac hypertrophy through
activating the PI3K-AKT-mTOR signaling pathway. Materials and Methods: The …
activating the PI3K-AKT-mTOR signaling pathway. Materials and Methods: The …
Cardiotoxicity and cardioprotection by artesunate in larval zebrafish
C Zheng, L Shan, P Tong, T Efferth - Dose-Response, 2020 - journals.sagepub.com
Although artesunate (ART) is generally accepted as a safe and well-tolerated first-line
treatment of severe malaria, cases of severe side effects and toxicity of this compound are …
treatment of severe malaria, cases of severe side effects and toxicity of this compound are …
Exercise training attenuates cardiac vulnerability and promotes cardiac resistance to isoproterenol-induced injury following hookah smoke inhalation in male rats: role …
Hookah smoking is on the rise around the world. Present study investigated the heart
resistance to harmful stress following long-term waterpipe tobacco smoking (WTS) and …
resistance to harmful stress following long-term waterpipe tobacco smoking (WTS) and …
Impact of a single bout of resistance exercise on serum Klotho in healthy young men
T Morishima, E Ochi - Physiological Reports, 2021 - Wiley Online Library
Background It has been shown that Klotho protects vascular endothelial function. Given that
a single bout of resistance‐exercise‐induced hypertensive stimulus causes endothelial …
a single bout of resistance‐exercise‐induced hypertensive stimulus causes endothelial …