Synthesis of 1-perfluoroalkyl-3-heteroaryl bicyclo [1.1. 1] pentanes via visible light-induced and metal-free perfluoroalkylation of [1.1. 1] propellane

B Yan, G Xu, H Han, J Hong, W Xu, D Lan, C Yu… - Green …, 2023 - pubs.rsc.org
Perfluoroalkyl groups containing bicyclo [1.1. 1] pentanes (BCPs) are gaining increasing
interest in the pharmaceutical industry and materials science; however, the development of …

[HTML][HTML] Strain-release transformations of bicyclo [1.1. 0] butanes and [1.1. 1] propellanes

QQ Hu, J Chen, Y Yang, H Yang, L Zhou - Tetrahedron Chem, 2024 - Elsevier
Abstract Bicyclo [1.1. 0] butanes (BCBs) and [1.1. 1] propellanes (tricyclo [1.1. 1.0 1, 3]
pentanes, TCPs) are structurally unique compounds with different chemical properties …

Photochemical tandem reaction of nitrogen containing heterocycles, bicyclo [1.1. 1] pentane, and difluoroiodane (iii) reagents

Y Zhu, F Yi, N Zhou, Y Zhang, Y Zhang… - Organic & Biomolecular …, 2024 - pubs.rsc.org
A visible light-induced difluoroalkylation/heteroarylation of [1.1. 1] propellane with nitrogen
containing heterocycles and difluoroiodane (III) reagents was achieved. Various …

Site-Specific Radical Alkylation of Aryl Cyanide: Visible-Light, Photoredox-Catalyzed, Three-Component Arylalkylation of [1.1. 1] Propellane

H Hou, S Guo, X Shen, C Chen, X Chen, H Yu… - Organic …, 2024 - ACS Publications
We report herein a three-component radical arylalkylation of [1.1. 1] propellane toward the
synthesis of aryl-substituted bicyclo [1.1. 1] pentane derivatives. The use of electron-deficient …

EDA Complex from BCP‐Thianthrenium Salt: A Catalyst‐Free Strategy To Access 1‐Trifluoromethyl‐3‐quinoxaline Derivatives Bicyclo [1.1. 1] pentanes

G Zhang, Z Luo, G Mei, H Wang… - European Journal of …, 2024 - Wiley Online Library
Abstract The construction of bicyclo [1.1. 1.] pentanes (BCPs) typically require the
cumbersome use of labile [1.1. 1.] propellane in solution and involve multicomponent radical …

Metal-and photocatalyst-free three-component strategy to prepare benzylalcohol-, aldehyde-substituted BCP building blocks

F Li, H Liao, J Dong, W Xiong, Y Yan, G Li, D Xue - Green Chemistry, 2024 - pubs.rsc.org
Bicyclo [1.1. 1] pentanes (BCPs), which can serve as bioisosteres of para-disubstituted
benzene rings, have emerged as useful bioactive scaffolds in drug discovery research …

[PDF][PDF] Egyszerű módszer propellán elektrofil aktiválására savakkal

G KRISTÓF - kemiatdk.elte.hu
A gyógyszeripar napjaink egyik legnagyobb iparága. A betegségek hatásainak kezelésén,
enyhítésén dolgozni privilégium. A tudomány fejlődésével párhuzamosan emiatt az …