Aging and urinary control: Alterations in the brain–bladder axis
CC Hardy, R Korstanje - Aging cell, 2023 - Wiley Online Library
Age‐associated alterations in bladder control affect millions of older adults, with a heavy
burden added to families both economically and in quality of life. Therapeutic options are …
burden added to families both economically and in quality of life. Therapeutic options are …
[HTML][HTML] Cancer-associated fibroblasts in bladder cancer: origin, biology, and therapeutic opportunities
Context Bladder cancer (BLCA) is a highly prevalent tumour and a health problem
worldwide, especially among men. Recent work has highlighted the relevance of the tumour …
worldwide, especially among men. Recent work has highlighted the relevance of the tumour …
Polyploid superficial uroepithelial bladder barrier cells express features of cellular senescence across the lifespan and are insensitive to senolytics
IM Al‐Naggar, M Antony, D Baker, L Wang… - Aging …, 2024 - Wiley Online Library
Lower urinary tract dysfunction (LUTD) increases with aging. Ensuing symptoms including
incontinence greatly impact quality of life, isolation, depression, and nursing home …
incontinence greatly impact quality of life, isolation, depression, and nursing home …
Defining the molecular fingerprint of bladder and kidney fibroblasts
G Apodaca - American Journal of Physiology-Renal …, 2023 - journals.physiology.org
Fibroblasts are integral to the organization and function of all organs and play critical roles in
pathologies such as fibrosis; however, we have limited understanding of the fibroblasts that …
pathologies such as fibrosis; however, we have limited understanding of the fibroblasts that …
Loss of resilience contributes to detrusor underactivity in advanced age
R Ramasamy, DS Baker, F Lemtiri-Chlieh… - Biogerontology, 2023 - Springer
Volume hyposensitivity resulting from impaired sympathetic detrusor relaxation during
bladder filling contributes to detrusor underactivity (DU) associated with aging. Detrusor …
bladder filling contributes to detrusor underactivity (DU) associated with aging. Detrusor …
The hyperpolarization-activated, cyclic nucleotide-gated channel resides on myocytes in mouse bladders and contributes to adrenergic-induced detrusor relaxation
F Lemtiri-Chlieh, DS Baker… - American Journal …, 2022 - journals.physiology.org
Control of urinary continence is predicated on sensory signaling about bladder volume.
Bladder sensory nerve activity is dependent on tension, implicating autonomic control over …
Bladder sensory nerve activity is dependent on tension, implicating autonomic control over …
[HTML][HTML] Deconstructing Organs: Single-Cell Analyses, Decellularized Organs, Organoids, and Organ-on-a-Chip Models: The hyperpolarization-activated, cyclic …
F Lemtiri-Chlieh, DS Baker, IM Al-Naggar… - American Journal of …, 2022 - ncbi.nlm.nih.gov
Control of urinary continence is predicated on sensory signaling about bladder volume.
Bladder sensory nerve activity is dependent on tension, implicating autonomic control over …
Bladder sensory nerve activity is dependent on tension, implicating autonomic control over …