Single-cell RNA sequencing (scRNA-Seq) is a recent technology that allows for the
measurement of the expression of all genes in each individual cell contained in a sample …

Undoubtedly, single-cell RNA sequencing (scRNA-seq) has changed the research
landscape by providing insights into heterogeneous, complex and rare cell populations …

Background Computational cell type deconvolution enables the estimation of cell type
abundance from bulk tissues and is important for understanding tissue microenviroment …

Background: Neuroblastoma (NB) is a childhood cancer originating from immature nerve
cells in the sympathetic nervous system. Current clinical and molecular subtyping methods …

The diagnostic spectrum for AML patients is increasingly based on genetic abnormalities
due to their prognostic and predictive value. However, information on the AML blast …

Background Cancer heterogeneity is a major challenge in clinical practice, and to some
extent, the varying combinations of different cell types and their cross-talk with tumor cells …

Background Like other cancers, considerable effort has been made in acute myeloid
leukemia (AML) to identify prognostic genes and long noncoding RNAs (lncRNAs) with their …

Background: Previous studies have reported that genes highly expressed in leukemic stem
cells (LSC) may dictate the survival probability of patients and expression-based cellular …

Simple Summary The second most common childhood leukemia, acute myeloid leukemia
(AML), is a heterogeneous disease with a poor prognosis. In order to improve outcomes …

Owing to their functional diversity in many cancers, long noncoding RNAs (lncRNAs) are
receiving special attention. LncRNAs not only function as oncogenes or tumor suppressors …