After ischemic stroke, survivors experience motor dysfunction and deterioration of memory
and cognition. These symptoms are associated with the disruption of normal neuronal …

Designing translational antioxidative agents that could scavenge free radicals produced
during reperfusion in brain ischemia stroke and alleviate neurologic damage is the main …

Drug delivery to the brain is crucial in the treatment for central nervous system disorders.
While significant progress has been made in recent years, there are still major challenges in …

Background: Ischemic heart diseases are leading causes of death and reduced life quality
worldwide. Although revascularization strategies significantly reduce mortality after acute …

Subarachnoid hemorrhage (SAH) is a severe subtype of stroke caused by the rupturing of
blood vessels in the brain. The ability to accurately assess the degree of bleeding in an SAH …

Ischemic encephalopathy is associated with a high mortality and rate of disability. The most
common type of ischemic encephalopathy, ischemic stroke, is the second leading cause of …

Pyroptosis mediates neuroinflammation following ischemic stroke and contributes to its
development, indicating that targeting pyroptosis-related pathways could be a potential …

The combined use of two or more different drugs can better promote nerve recovery and its
prognosis for treatment of stroke. The salvianolate lyophilized injection (SLI) and …

Reperfusion after cerebral ischemia leads to secondary damage to the nervous system,
called cerebral ischemia/reperfusion injury (CIRI). The blood–brain barrier (BBB) consists of …

Background: Ischemic heart disease is the leading cause for death and disability worldwide
and predominantly manifests as acute myocardial infarction (AMI). Current standard of care …