[HTML][HTML] Integrated data envelopment analysis, multi-criteria decision making, and cluster analysis methods: Trends and perspectives
Abstract Data Envelopment Analysis (DEA), Multi-criteria Decision Analysis (MCDA), and
Cluster Analysis (CA) are techniques widely used to help decision-makers determine the …
Cluster Analysis (CA) are techniques widely used to help decision-makers determine the …
Dysregulation of RNA splicing in early non-alcoholic fatty liver disease through hepatocellular carcinoma
While changes in RNA splicing have been extensively studied in hepatocellular carcinoma
(HCC), no studies have systematically investigated changes in RNA splicing during earlier …
(HCC), no studies have systematically investigated changes in RNA splicing during earlier …
Hepatocyte deletion of IGF2 prevents DNA damage and tumor formation in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. Serine‐
arginine rich splicing factor 3 (SRSF3) plays a critical role in hepatocyte function and its loss …
arginine rich splicing factor 3 (SRSF3) plays a critical role in hepatocyte function and its loss …
CFIm-mediated alternative polyadenylation remodels cellular signaling and miRNA biogenesis
The mammalian cleavage factor I (CFIm) has been implicated in alternative polyadenylation
(APA) in a broad range of contexts, from cancers to learning deficits and parasite infections …
(APA) in a broad range of contexts, from cancers to learning deficits and parasite infections …
Immunological significance of prognostic alternative splicing signature in hepatocellular carcinoma
Q Xu, H Xu, R Deng, N Li, R Mu, Z Qi, Y Shen… - Cancer cell …, 2021 - Springer
Background Hepatocellular carcinoma (HCC) ranks the sixth prevalent tumors with high
mortality globally. Alternative splicing (AS) drives protein diversity, the imbalance of which …
mortality globally. Alternative splicing (AS) drives protein diversity, the imbalance of which …
Comprehensive analysis and establishment of a prediction model of alternative splicing events reveal the prognostic predictor and immune microenvironment …
S Yu, C Hu, L Liu, L Cai, X Du, Q Yu, F Lin… - Journal of Translational …, 2020 - Springer
Background Triple-negative breast cancer (TNBC) is widely concerning because of high
malignancy and poor prognosis. There is increasing evidence that alternative splicing (AS) …
malignancy and poor prognosis. There is increasing evidence that alternative splicing (AS) …
[HTML][HTML] Integrative analysis identifies key mRNA biomarkers for diagnosis, prognosis, and therapeutic targets of HCV-associated hepatocellular carcinoma
Y Zhang, Y Tang, C Guo, G Li - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
Hepatitis C virus-associated HCC (HCV-HCC) is a prevalent malignancy worldwide and the
molecular mechanisms are still elusive. Here, we screened 240 differentially expressed …
molecular mechanisms are still elusive. Here, we screened 240 differentially expressed …
[HTML][HTML] A comprehensive characterization of alternative splicing events related to prognosis and the tumor microenvironment in lung adenocarcinoma
S Ma, J Zhu, M Wang, T Han, J Zhu… - Annals of Translational …, 2022 - ncbi.nlm.nih.gov
Background Alternative splicing (AS) is a critical mechanism of post-transcriptional
regulation and has been widely reported to be associated with the tumor progression and …
regulation and has been widely reported to be associated with the tumor progression and …
A novel 16-gene alternative mRNA splicing signature predicts tumor relapse and indicates immune activity in stage I–III hepatocellular carcinoma
XX Chen, BH Zhang, YC Lu, ZQ Li, CY Chen… - Frontiers in …, 2022 - frontiersin.org
Background: Hepatocellular carcinoma (HCC) is a lethal disease with high relapse and
dismal survival rates. Alternative splicing (AS) plays a crucial role in tumor progression …
dismal survival rates. Alternative splicing (AS) plays a crucial role in tumor progression …
A systems biology‐based approach to screen key splicing factors in hepatocellular carcinoma
R Zhu, X Wang, Q Yu, W Guo… - Molecular Carcinogenesis, 2023 - Wiley Online Library
A splicing factor is as an important upstream regulator of the alternative splicing process.
Hence, it is considered to be a therapeutic target for hepatocellular carcinoma (HCC) …
Hence, it is considered to be a therapeutic target for hepatocellular carcinoma (HCC) …