Targeting αvβ3 integrin: design and applications of mono-and multifunctional RGD-based peptides and semipeptides

L Auzzas, F Zanardi, L Battistini… - Current medicinal …, 2010 - ingentaconnect.com
The outstanding physio-pathological role played by integrin receptors in living subjects
motivates the enormous interest shown by scientists worldwide for this topic. More than …

Molecular dynamics simulations of cRGD-conjugated PEGylated TiO2 nanoparticles for targeted photodynamic therapy

P Siani, G Frigerio, E Donadoni… - Journal of Colloid and …, 2022 - Elsevier
The conjugation of high-affinity cRGD-containing peptides is a promising approach in
nanomedicine to efficiently reduce off-targeting effects and enhance the cellular uptake by …

Antimicrobial titanium surface via click-immobilization of peptide and its in vitro/vivo activity

J Chen, Y Zhu, M Xiong, G Hu, J Zhan, T Li… - ACS Biomaterials …, 2018 - ACS Publications
The use of antimicrobial peptides (AMPs)-functionalized titanium implants is an efficient
method for preventing bacterial infection. However, the attachment of AMPs to the surface of …

Osseous response on linear and cyclic RGD‐peptides immobilized on titanium surfaces in vitro and in vivo

M Heller, VV Kumar, A Pabst, J Brieger… - … Research Part A, 2018 - Wiley Online Library
Biomimetic surface modifications of titanium (Ti) implants using the Arg‐Gly‐Asp‐sequence
(RGD) are promising to accelerate bone healing in cases of medical implants. Therefore, we …

Mechanism of RGD-conjugated nanodevice binding to its target protein integrin α V β 3 by atomistic molecular dynamics and machine learning

G Frigerio, E Donadoni, P Siani, J Vertemara, S Motta… - Nanoscale, 2024 - pubs.rsc.org
Active targeting strategies have been proposed to enhance the selective uptake of
nanoparticles (NPs) by diseased cells, and recent experimental findings have proven the …

Resonant infrared multiphoton dissociation spectroscopy of gas-phase protonated peptides. Experiments and Car–Parrinello dynamics at 300 K

G Gregoire, MP Gaigeot, DC Marinica… - Physical Chemistry …, 2007 - pubs.rsc.org
The gas-phase structures of protonated peptides are studied by means of resonant infrared
multiphoton dissociation spectroscopy (R-IRMPD) performed with a free electron laser. The …

[PDF][PDF] Immobilisation of linear and cyclic RGD-peptides on titanium surfaces and their impact on endothelial cell adhesion and proliferation

PW Kämmerer, M Heller, J Brieger, MO Klein… - Eur Cell …, 2011 - academia.edu
Functional coatings on titanium vascular stents and endosseous dental implants could
probably enhance endothelial cell (EC) adhesion and activity with a shortening of the wound …

Identification of an endogenously generated cryptic collagen epitope (XL313) that may selectively regulate angiogenesis by an integrin yes-associated protein (YAP) …

JJ Ames, L Contois, JM Caron, E Tweedie… - Journal of Biological …, 2016 - ASBMB
Extracellular matrix (ECM) remodeling regulates angiogenesis. However, the precise
mechanisms by which structural changes in ECM proteins contribute to angiogenesis are …

Biomimetic poly (amidoamine) hydrogels as synthetic materials for cell culture

E Jacchetti, E Emilitri, S Rodighiero, M Indrieri… - Journal of …, 2008 - Springer
Abstract Background Poly (amidoamine) s (PAAs) are synthetic polymers endowed with
many biologically interesting properties, being highly biocompatible, non toxic and …

Radiotracers for different angiogenesis receptors in a melanoma model

ÉA Oliveira, BL Faintuch, EGF Núñez… - Melanoma …, 2012 - journals.lww.com
Early and reliable diagnosis of melanoma, a skin tumor with a poor prognosis, is extremely
important. Phage display peptide libraries are a convenient screening resource for …