Actinobacteria constitute a highly diverse bacterial phylum with an unrivalled metabolic
versatility. They produce most of the clinically used antibiotics and a plethora of other natural …

Streptomycetes are the most abundant source of antibiotics. Typically, each species
produces several antibiotics, with the profile being species specific. Streptomyces coelicolor …

Actinobacteria are Gram-positive bacteria with high G+ C DNA content that constitute one of
the largest bacterial phyla, and they are ubiquitously distributed in both aquatic and …

Covering: 2000 to 2018 The antimicrobial activity of many of their natural products has
brought prominence to the Streptomycetaceae, a family of Gram-positive bacteria that …

Covering: up to early 2011 Streptomycetes and other actinobacteria are renowned as a rich
source of natural products of clinical, agricultural and biotechnological value. They are being …

Well-characterized promoters are essential tools for metabolic engineering and synthetic
biology. In Streptomyces coelicolor, the native kasO p is a temporally expressed promoter …

Polyketide synthases (PKSs) are multifunctional enzymes that catalyze the biosynthesis of a
huge variety of carbon chains differing in their length and patterns of functionality and …

Aerial mycelium formation is activated by extracellular regulatory proteins in Streptomyces
spp. These proteins act as morphogens and bring about morphological differentiation during …

BldD is a transcriptional regulator essential for morphological development and antibiotic
production in Streptomyces coelicolor. Here we identify the BldD regulon by means of …

Bacillus cereus UW85 produces two antibiotics that contribute to its ability to suppress
certain plant diseases (L. Silo-Suh, B. Lethbridge, SJ Raffel, H. He, J. Clardy, and J …